PURPOSE Sedentary behavior has been proposed as an independent cardio-metabolic risk factor even in adults who are physically active through recreational activity. Because little is known about the metabolic effects of sedentariness in seniors, the relationship between sedentary behavior and cardio-metabolic risk was examined in physically active older adults. METHODS Fifty-four community dwe...

BACKGROUND Unspecific symptoms often proceed a serious chronic disease condition long before the onset of the disease. The role of an unspecific premonitory symptom (UPMS) pattern as premonitory signs of subsequent type 2 diabetes mellitus (T2DM) diagnosis independent of established cardio-metabolic risk factors is unclear and therefore was examined in the present study. METHODS The study pop...

The risk of cardio vascular diseases can be identified by measuring the retinal blood vessel. The identification of wrong blood vessel may result in wrong clinical diagnosis. This proposed system addresses the problem of identifying the true vessel by vascular structure segmentation. In this proposed model the segmented vascular structure is modelled as a vessel segment graph and the true vesse...

Preservation of the mitral valve (MV) size is essential for function, and a reduced MV coaptation-zone area increases risk developing functional regurgitation (FMR). We aimed to determine if leaflet areas were associated with severity atherosclerosis assessed by cardio-ankle vascular index (CAVI) in patients normal left ventricle (LV) systolic function real-time 3D echocardiography (RT3DE).We p...

BACKGROUND The adverse health effects of abdominal obesity are well documented in adults, but such association remains to be determined in the pediatric age group. This study aims to perform a systematic review on the association between abdominal obesity and cardio-metabolic factors such as dyslipidemia, hypertension, and hyperglycemia among children and adolescents. MATERIALS AND METHODS A ...

Stoke is a very widespread disease, a leading cause of death, and generates high healthcare costs due to causing considerable disability. The aetiology and outcomes of stroke are various. Ischemic stroke dominates and differs pathogeneti-cally from haemorrhagic stroke, the latter having a poorer prognosis. Several modifiable risk factors, including hyper-tension, diabetes, hyperlipidemia, smoki...

Patients with haemophilia (PWH) are relatively protected from cardiovascular death. Recent insights have shown that this is not due to less formation of atherosclerosis than in non-haemophilic men, therefore protection from the final occlusive thrombus will be the major determinant. Prevalence and incidence rates of cardiovascular disease (especially non-fatal events) are scarce, although ongoi...

BACKGROUND Urban South-Asian's are predisposed to early onset of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). There is an urgent need for country specific primary prevention strategies to address the growing burden of cardio-metabolic disease in this population. The aim of this clinical trial is to evaluate whether intensive (3-monthly) lifestyle modification advice is supe...

BACKGROUND The present study was designed to evaluate association of psychosocial distress with cardio metabolic risk factors and liver enzymes in Iranian children and adolescents. METHOD This nationwide study was conducted as the third survey of the school-based surveillance system that was conducted among 5593 school students, 10-18 years in Iran. High triglyceride (TG), high fasting blood ...