Blood oxygenation level-dependent (BOLD) imaging is firmly established as a powerful tool for clinical and research studies in the brain. Though, borrowing from the brain methodology, the technique was early adapted for the heart, due to artifacts unique to myocardial imaging; cardiac and respiratory motion, flow and blood pool effects, and magnetic susceptibility effects arising from the adjac...

A. Sigfridsson, J-P. E. Kvitting, L. Wigström, H. Knutsson Division of Clinical Physiology, Linköping University, Linköping, Sweden, Biomedical Engineering, Linköping University, Linköping, Sweden Introduction: The recently introduced k-t BLAST technique [1] for accelerating acquisition of dynamic imaging has shown promising results. By exploiting lower temporal frequency content in parts of th...

Coronary artery disease is the leading cause of death in advanced countries. Early detection and diagnosis of coronary artery disease plays an important role in the identification of disease severity and prediction of disease outcome, consequently improving patient management. Diagnosis and management of coronary artery disease is increasingly dependent on less-invasive imaging modalities, incl...

Since it’s original proposal by Mansfield et al. in 1977 [1], echo-planar imaging (EPI) has had a key role in the evolution of cardiac MRI. EPI involves the rapid acqusition of k-space data in a raster-like fashion, requiring a fewer number of excitations compared to conventional 2DFT imaging. This is crucial in cardiac imaging as respiratory and cardiac motion places high demands on imaging sp...

PURPOSE Micro-CT is widely used for small animal imaging in preclinical studies of cardiopulmonary disease, but further development is needed to improve spatial resolution, temporal resolution, and material contrast. We present a technique for visualizing the changing distribution of iodine in the cardiac cycle with dual source micro-CT. METHODS The approach entails a retrospectively gated du...