background: nt-probnp is a marker that is released from ventricles in response to pressure and volume overload. raised plasma level of nt-probnp is seen in ventricular dysfunction, ventricular muscular mass reduction or ventricular ischemia. anthracyclines are widely used in treatment of pediatric cancer but their use is associated with cardiotoxicity which increases mortality and morbidity. we...

leiomyosarcoma is one of the soft tissue sarcomas that could originate from different parts of body and are mostly presented as retropritoneal mass. leiomyosarcomas of vascular origin are particularly rare tumors occurring mainly in inferior vena cava (ivc). here, we report the case of a 35-year-old male patient who presented with ascites and jaundice. further evaluation revealed large hepatic ...

conclusions the authors emphasize on the rarity of this pathology among children, its clinical polymorphism, the necessity of a rapid diagnosis, and an appropriate treatment to avoid complications and recurrence of the tumor. introduction right atrial myxoma is a rare disease among children and its clinical presentation is not specific. case presentation we reported a four-year-old girl with ex...

conclusions: this study showed acceptable sensitivity and specificity of qtcd and qtd in comparison to lvmi; it seems that standard ecg can be used for early diagnosis of cardiac involvement in asymptomatic patients with thalassemia major. patients and methods: in a case-control study, 60 patients older than ten years of age with thalassemia major who received regular blood transfusion and iron...

idiopathic hypereosinophilic syndrome represents a heterogeneous group of leukoprolifrative disorders associated with prolonged eosinophilia of an undetectable cause with multi organ system dysfunction. it is a rare group disorder in children, most cases are reported in adult age group. we report a child with this syndrome who along with the usual features of the syndrome also had the presentat...

conclusion the myocardial grayscale intensity, velocity and displacement can effectively reflect the situation of steiri in patients after cardiac operation, and ti (cvi) has a higher performance in discriminating between patients with and without steiri. background the timely diagnosis of presence or absence of reperfusion injury after cardiac operation is critical for the patient’s outcome. w...

buckwheat rutin has been found to be able to inhibit angiotensin ii (angii) - induced hypertrophy in cultured neonatal rat cardiomyocytes, but the mechanism remains uncertain. in this study, myocardial hypertrophy model was made by adding angii to the medium of cardiac myocytes of neonatal rats, meanwhile, different concentrations of buckwheat rutin were applied to observe their effects. intrac...

background: differences in the quantity and distribution of coronary veins between patients with ischemic and non-ischemic cardiomyopathy might affect the potential for the left ventricular (lv) lead targeting in patients undergoing cardiac resynchronization therapy (crt). in the current study, we assessed and compared the suitability of the coronary venous system for the lv lead placement in i...

to improve the specificity of biochemical markers of myocardial infarction (mi) a method to measure cardiac troponin-i (ctn-i) was developed. ctn-i is a protein unique to cardiac muscle and is released after mi. consecutive 150 patients admitted to the coronary care unit was studied. value of ctn-i was determined in all samples. ctn-i concentration in the mi patients group was increased compare...

regular participation in intensive physical exercise is associated with electro-morphological changes in the heart.   this benign process is called athlete’s heart. athlete’s heart resembles few pathologic conditions in some aspects. so differentiation of these conditions is very important which otherwise may lead to a catastrophic event such as sudden death. the most common causes of sudden de...