A 49-year-old man with carcinoid tumor of the thymus presented with the clinical picture of acute pericarditis. Recurrent bouts persisted after removal of the tumor without other evidence to indicate tumor recurrence. There were no associated manifestations of an endocrine disorder.

A primary carcinoid tumor of the thymus showing ectopic ACTH syndrome was evaluated scintigraphically with four radiopharmaceuticals and a fluorescence method. Iodine-123-MIBG and 201Tl-Cl scintigraphy clearly demonstrated the tumor. Gallium-67-citrate and 99mTc(V)-DMSA showed no tumor uptake. The fluorescence method confirmed numerous storage granules of norepinephrine. Iodine-123-MIBG scintig...

A 77-year-old woman was admitted to our hospital because of a mass lesion in the left lung. The tumor was pulmonary carcinoid associated with sarcoid reactions in the regional lymph nodes and scattered in the resected lung parenchyma. Pulmonary carcinoid with sarcoid reactions is extremely rare. This appears to be the first case report in which tumor-related sarcoid reactions were studded withi...

THE CARCINOID TUMOR is a slow growing malignant lesion capable of distant metastases. Frequently, patients afflicted with this tumor develop a pathognomonic fibrosis of valves and endocardium involving primarily the right side of the heart. Although only 50% of the patients with metastatic disease survive for 3 years, these patients usually succumb from intractable congestive heart failure.' Re...

Ectopic production of adrenocorticotropic hormone by carcinoid tumors is relatively uncommon and may not be recognized by physicians. This report describes a woman who had Cushing syndrome from the ectopic secretion of adrenocorticotropic hormone by a carcinoid tumor. Her cause of death was a pneumonia that may have been secondary to her untreated hypercortisolism. There are threeinstructive el...

PURPOSE The carcinoid tumor was recently categorized as a malignant disease due to its possibility of metastasis. This study was aimed to investigate the clinical characteristics and the metastatic rate of colorectal carcinoid tumors. METHODS Charts were reviewed for 502 patients diagnosed with and treated for colorectal carcinoid tumors between January 2006 and December 2009. The location, s...

A 21-year-old woman with Cushing's syndrome presented with a mediastinal tumor. Ectopic ACTH syndrome was diagnosed and the tumor was resected. The histopathological diagnosis was thymic atypical carcinoid. Despite all tumor lesions having been resected, the tumor relapsed and multiple metastatic lesions grew aggressively. Combination chemotherapy with cisplatin and etoposide (VP16) was adminis...

THE CARCINOID TUMOR is a slow growing malignant lesion capable of distant metastases. Frequently, patients afflicted with this tumor develop a pathognomonic fibrosis of valves and endocardium involving primarily the right side of the heart. Although only 50% of the patients with metastatic disease survive for 3 years, these patients usually succumb from intractable congestive heart failure.' Re...

Carcinoid tumors are neuroendocrine malignancies that frequently metastasize and secrete hormones that cause debilitating symptoms in patients. In this study we report the effects of valproic acid (VPA), a drug long used for the treatment of epilepsy, on the growth and neuroendocrine phenotype of human carcinoid cancer cells. VPA treatment of gastrointestinal and pulmonary carcinoid cells resul...