The production of carboxylic acids by partial wet oxidation of alkali lignin at elevated temperatures and pressures was studied experimentally. Two different heteropoly acids, phosphotungstic acid (H₃PW12O40) and phosphomolybdic acid (H₃PMo12O40), were used to catalyze the oxidation of lignin under hydrothermal conditions. Factors influencing the total yield of carboxylic acids formed during th...

GABA(A) receptors (GABA(A)Rs) have long been a focus as targets for alcohol actions. Recent work suggests that tonic GABAergic inhibition mediated by extrasynaptic δ subunit-containing GABA(A)Rs is uniquely sensitive to ethanol and enhanced at concentrations relevant for human alcohol consumption. Ethanol enhancement of recombinant α4β3δ receptors is blocked by the behavioral alcohol antagonist...

Malaria still remains a life-threatening parasitic disease with universal targets set for control and elimination. This study aimed to evaluate the in vitro antimalarial susceptibility of Plasmodium falciparum isolates berghei selected agents column chromatographic subfractions Glyphaea brevis leaves extract FTIR GCMS SF8. Trager Jensen as well World Health Organisation (WHO) standardised micro...

Carboxylic acids, amides and imides are key organic systems which provide understanding of molecular recognition and binding phenomena important in biological and pharmaceutical settings. In this context, studies of their mutual interactions and compatibility through co-crystallization may pave the way for greater understanding and new applications of their combinations. Extensive co-crystalliz...