We studied the effects of five high-fat semi-purified diets varying at a 4% (w/w) level in either stearic, oleic, linoleic, alpha-linolenic, or gamma-linolenic acid on body fat and energy metabolism in BALB/c mice. A diet containing caprylic, capric, lauric, and myristic acid was used as a reference diet and a diet with 4% conjugated linoleic acid (CLA) was used as a positive control as it is k...

Background. Pathogenetic factors that cause the development of inflammatory bowel diseases (IBD) remain poorly understood, namely, peculiarities saturated fatty acids (SFAs) in blood serum at different degrees disease severity, which is quite an important task. Objective: to evaluate level SFAs depending on IBD severity. Materials and methods. Thirty-seven patients with were examined, their ave...

There is an extensive literature dealing with t,he utilization by the animal body of various complex natural triglycerides, but up to the present time little attention has been paid to the separation and study of the individual fat,ty components for their ability t,o supply energy and support growth. There is no apparent reason to suppose that the individual components of a fat should be any le...

Phosphotriesterase (PTE) activities in mammalian serum are typically found in the lipoprotein fraction. This PTE requires Ca++ for activity and is consequently inactivated by ethylenediaminetetraacetic acid (EDTA). There is also a little known PTE in mammal serum that is resistant to EDTA inactivation. In this work, the PTE activities for the substrates O-hexyl O-2, 5-dichlorophenyl phosphorami...

In vivo human studies are considered to be the “gold standard” when investigating (trans)dermal delivery of actives. Previously, we reported effects a range vehicles on niacinamide (NIA) using conventional Franz cell studies. present work, dermal NIA was investigated in subjects confocal Raman spectroscopy (CRS) and tape stripping (TS). The included propylene glycol (PG), Transcutol® P (TC), bi...