نتایج جستجو برای: cantharidin

تعداد نتایج: 329  

Journal: :Environmental Health Perspectives 2003
Shu Zhang Chunhua Qin Stephen H Safe

Chemoprotective phytochemicals exhibit multiple activities and interact with several cellular receptors, including the aryl hydrocarbon (Ah) receptor (AhR). In this study we investigated the AhR agonist/antagonist activities of the following flavonoids: chrysin, phloretin, kaempferol, galangin, naringenin, genistein, quercetin, myricetin, luteolin, baicalein, daidzein, apigenin, and diosmin. We...

Journal: :International journal of molecular medicine 2006
Stanton Hon Lung Kok Chung Hin Chui Wing Sze Lam Jien Chen Fung Yi Lau Raymund Siu Ming Wong Gregory Yin Ming Cheng Wing Ka Tang Ivy Tuang Ngo Teo Filly Cheung Chor Hing Cheng Albert Sun Chi Chan Johnny Cheuk On Tang

Cantharidin isolated from Mylabris caraganae and other insects has been used as an anti-cancer drug in China for many years. However, its toxicity on the renal system and suppression effect on bone marrow limits its usage clinically. A synthetic analogue of cantharidin (CAN 037) has been shown to have cytotoxic effect on the SK-Hep 1 hepatoma cell line but its underlying working principle remai...

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