Cancer is a ruthless disease that has no definite cure and it very consequential to treat it. Chemotherapy other cancer treatments have lasting negative effects on patients, like fatigue, diarrhea, nausea, many harmful side effects. To decrease the time period of vigorous chemotherapy, should be detected early. Pathologists clinicians used methods diagnosis over years, but do this, large amount...

OBJECTIVES The benefits of PSA (prostate specific antigen)-testing in prostate cancer remain controversial with a consequential need for validation of additional biomarkers. We used highly standardized reverse-transcription (RT)-PCR assays to compare transcript levels of 10 candidate cancer marker genes - BMP6, FGF-8b, KLK2, KLK3, KLK4, KLK15, MSMB, PCA3, PSCA and Trpm8 - in carefully ascertain...

OBJECTIVE The purpose of the study is to highlight the use of gamma-glutamyl transpeptidase (GGT) as salivary enzyme tumor marker and assess the activity and concentration of GGT in precancerous and cancer patients and compare it with the normal control. MATERIALS AND METHODS Individuals in the age group of above 20 years were included in the study. In this study, salivary GGT was analyzed in...

The public can be defined as a mosaic consisting of various ethnic, religious and other social groups, hence the definition of public includes each individual persona. Public opinion is the voice of such public and is, therefore, considered a worthy element in political and economic discourse. Media can do much in providing education necessary for informing the public about cancerous substances...

recent studies on wavelet transform and fractal modeling applied on mammograms for the detection of cancerous tissues indicate that microcalcifications and masses can be utilized for the study of the morphology and diagnosis of cancerous cases. it is shown that the use of fractal modeling, as applied to a given image, can clearly discern cancerous zones from noncancerous areas. in this paper, f...

Over the past decade, investigators have increased their understanding of the genetic alteration that transforms a normal cell into one that is cancerous. One gene found to play a critical role in preventing the cancerous transformation of a cell is a tumor suppressor gene known as p53. If this gene is deactivated, a cell will become cancerous. Therefore, methods for reintroducing this gene bac...

In this study, we measured free radicals and thiobarbituric acid-reactive substances (TBARS) in hepatocellular carcinoma and in non-cancerous liver parenchyma. There was a higher concentration of free radicals in malignant tissue than in non-cancerous tissue. In contrast, the level of TBARS was significantly (P < 0.01) lower than non-cancerous liver parenchyma. These paradoxical results suggest...

Understanding cell proliferation mechanisms has been a long-lasting goal of the scientific community and specifically of cancer researchers. Previous genome-scale studies of cancer proliferation determinants have mainly relied on knockdown screens aimed to gauge their effects on cancer growth. This powerful approach has several limitations such as off-target effects, partial knockdown, and mask...