Cancer-related fatigue is the most prevalent and distressing symptom experienced by patients with advanced cancer. Central nervous system stimulants have been shown to relieve fatigue in nonmalignant disease. Modafinil is a stimulant with a selective site of action in the brain that is better tolerated than traditional stimulants, such as methylphenidate. The aim of this study was to determine ...

BACKGROUND Blood transfusions are often used as a potential treatment for cancer-related fatigue in anaemic palliative care patients. However, evidence of benefit using validated outcomes measures is lacking. AIM The aim of this study was to test the feasibility of using two such tools; the Brief Fatigue Inventory and FACT F-fatigue subscale, to measure change in fatigue following a blood tra...

PURPOSE/OBJECTIVES To determine the relationship between fatigue and physical activity in older patients with cancer. DESIGN Targeted analysis using data from a prospective longitudinal study. SETTING A cancer care facility in southeastern Ontario, Canada. SAMPLE 440 patients, aged 65 years and older, seeking consultation for cancer treatment at a regional cancer clinic for lymphoma or le...

Introduction: Fatigue is considered a reversible change of biological and psychic functions originated from the organism’s unbalance. In patients with cancer, fatigue usually reported as one most frequent symptoms defined chronic mainly in cases when metastases impair daily life activities significantly. Objective: This work aimed to evaluate prevalence head neck cancer submitted radiochemother...

Cancer-related fatigue has a significant impact on patients' physical and psychosocial functioning, symptom distress, and quality of life, yet it remains under-recognized and undertreated. The Oncology Nursing Society's Putting Evidence Into Practice initiative sought to improve patient outcomes relative to this important problem by critically examining and summarizing the evidence base for int...

In view of the large body of research demonstrating that optimism has beneficial effects on people’s well-being and health, one may assume that it also protects against fatigue. However, few studies have investigated the association between optimism and cancer-related fatigue in cancer patients, and the results are inconsistent. Thus our aim was to investigate if optimism is associated with sev...

PURPOSE/OBJECTIVES To determine whether clinical characteristics, physical fitness, or physical activity predict fatigue in older, long-term breast cancer survivors. DESIGN Cross sectional. SETTING National Cancer Institute-designated cancer center in Portland, OR. SAMPLE 47 women (X age = 69 years) who were at least one year beyond treatment completion, including surgery, radiation, chem...