Introduction Breast cancer continues to be an important health problem. Early detection is needed to improve prognosis and significantly reduce women mortality. Computer-Aided Diagnosis systems (CAD) can help radiologist to improve their ability to detect and classify breast lesions. However, automated interpretation of mammogram lesions still remains very difficult. Some of the reasons are the...

Scavenger receptor class B type I (SR-BI) mediates the selective uptake of HDL cholesteryl esters (CEs) and facilitates the efflux of unesterified cholesterol. SR-BI expression in macrophages presumably plays a role in atherosclerosis. The role of SR-BI for selective CE uptake and cholesterol efflux in macrophages was explored. Macrophages and HDL originated from wild-type (WT) or SR-BI knockou...

Ultrasound imaging plays an important role in breast lesion differentiation. However, diagnostic accuracy depends on ultrasonographer experience. Various computer aided diagnosis systems has been developed to improve breast cancer detection and reduce the number of unnecessary biopsies. In this study, our aim was to improve breast lesion classification based on the BI-RADS (Breast Imaging Repor...

Infection of hepatocytes by Plasmodium falciparum sporozoites requires the host tetraspanin CD81. CD81 is also predicted to be a coreceptor, along with scavenger receptor BI (SR-BI), for hepatitis C virus. Using SR-BI-knockout, SR-BI-hypomorphic and SR-BI-transgenic primary hepatocytes, as well as specific SR-BI-blocking antibodies, we demonstrate that SR-BI significantly boosts hepatocyte perm...

Today business intelligence (BI) systems, which provide management with decision-supportive information, are considered to be a prerequisite for organizational success. In contrast to the operation of BI, BI system management is still an emerging topic in information systems (IS) research. Even though the cost management of BI systems is highly relevant for practice, the field is widely unexplo...

The paper examines how a retail organisation transformed from home-made Business Intelligence (BI) to a mature BI-based organisation, over a decade long period of time. We engaged in an Action Research (AR) inquiry where the transformation was explored through the first-hand experiences of one of the co-authors. Concepts from the organisational learning theory are used to analyse the organisati...

Although many IT and business managers today may be lured into business intelligence (BI) investments by the promise of predictive analytics and emerging BI trends, creating an enterprise-wide BI capability is a journey that takes time. This article describes Norfolk Southern Railway’s BI journey, which began in the early 1990s with departmental reporting, evolved into data warehousing and anal...

OBJECTIVE To retrospectively investigate the diagnostic value of breast MRI in patients with BI-RADS 3-5 microcalcifications in mammography. METHODS Eighty-four patients with BI-RADS 3-5 microcalcifications on mammography underwent breast MR exams before surgical biopsy with a hookwire position under mammographic guidance. Two radiologists reviewed each lesion with BI-RADS by consensus. The d...

The incorporation of Bi in GaSb1 xBix alloys grown by molecular beam epitaxy is investigated as a function of Bi flux at fixed growth temperature (275 1C) and growth rate ð1 μm h Þ. The Bi content is found to vary proportionally with Bi flux with Bi contents, as measured by Rutherford backscattering, in the range 0oxr4:5%. The GaSbBi samples grown at the lowest Bi fluxes have smooth surfaces fr...

Business Intelligence (BI) is one of the fastest growing software sector and software vendors are rapidly developing multiple BI tools to support the growing data analysis needs of organisations. In order to be sustainable in a briskly changing turbulent environment, organisations need to have access to information about their operational performance. BI tools play a vital role in supporting th...