BACKGROUND Calvarial hemangiomas are one of the rarest neoplasms affecting the skull, predominantly occurring in parietal and frontal bones. CASE DESCRIPTION We report a parietal hemangioma in a middle-aged female which presented as a painless swelling that was progressively increasing in size and was treated surgically. CONCLUSION Although rare, calvarial hemangioma should be a part of the...

The bone and immune systems are closely interconnected. The immediate inflammatory response after fracture is known to trigger a healing cascade which plays an important role in bone repair. Toll-like receptor 4 (TLR4) is a member of a highly conserved receptor family and is a critical activator of the innate immune response after tissue injury. TLR4 signaling has been shown to regulate the sys...

To cite: Saba R, Senussi MH, Alwakkaf A, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013010165 DESCRIPTION An 18-year-old-man, with no relevant medical history, presented to the outpatient clinic for the evaluation of chronic headache. The patient described a waxing waning pressure sensation in the occipital area that had started a few months prior, an...

BACKGROUND AND PURPOSE The osteogenic potency of erythropoietin (EPO) has been documented. However, its efficacy in a large-animal model has not yet been investigated; nor has a clinically safe dosage. The purpose of this study was to overcome such limitations of previous studies and thereby pave the way for possible clinical application. Our hypothesis was that EPO increases calvarial bone hea...

PURPOSE Micro-computed tomography (micro-CT) has been widely used in the evaluation of regenerated bone tissue but the reliability of micro-CT has not yet been established. This study evaluated the correlation between histomorphometric analysis and micro-CT analysis in performing new bone formation measurement. METHODS Critical-size calvarial defects were created using a 8 mm trephine bur in ...

BACKGROUND Reconstruction of scalp and calvarial defects after tumor ablation frequently requires prosthetic cranioplasty and cutaneous coverage. Furthermore, patients often have advanced disease and receive perioperative radiotherapy. We evaluated the complications of scalp reconstruction with a free latissimus dorsi muscle flap in this setting. METHODS The complications and the oncologic an...

INTRODUCTION In extreme situations in which the extent of bone loss or damage is too large, complete regeneration will not occur. Such bone defects in the craniofacial complex are often a result of trauma or cancer surgery. Approximately 1,600,000 bone grafts are performed each year to regenerate bone loss due to trauma or disease; 6% of these (96,000) are cranio-maxillofacial in nature. Autolo...

OBJECTIVES This study was undertaken to evaluate the effect of hyperbaric oxygen (HBO) on the repair of critical-sized defects in the presence and absence of a nonvascularized autogenous bone graft. STUDY DESIGN Ten New Zealand White rabbits were randomly divided into 2 groups of 5 animals each. Bilateral 15-mm calvarial defects were created in the parietal bones of each animal, resulting in ...