three major flavonoid fractions were separated from a methanol extract of calendula officinalis flowers by preparative tlc. these fractions were evaluated for the inhibition of parent and tamoxifen resistant t47d human breast cancer cells. we also examined the effect of quercetin and isorhamnetin on the growth of parent and resistant t47d cells in the presence and absence of tamoxifen. it was f...

effect of gibberellic acid on marigold (calendula officinalis l.) was evaluated in a pot culture experiment. a factorial experiment based on completely randomized design including 12 treatments and four replications was carried out. main factor was foliar application stages (first, second and third) and sub factor included different concentrations of ga3 (0, 50, 150 and 250 mg l-1). results sho...

Effect of Calendula officinalis flower extract was investigated against experimentally induced thermal burns in rats. Burn injury was made on the shaven back of the rats under anesthesia and the animals were treated orally with different doses of the flower extract (20 mg, 100 mg and 200 mg/kg body weight). The animals treated with the extract showed significant improvement in healing when comp...

BACKGROUND Currently a chronic inflammation is considered to be the one of the most important reasons of the atherosclerosis progression. A huge amount of researches over the past few decades are devoted to study the various mechanisms of inflammation in the development of atherosclerotic lesions. PURPOSE To review current capabilities of anti-inflammatory therapy for the prevention and treat...

Marigold belongs to the oldest medicinal plants, which had been used in the ancient times. At present it supplies its material of a great significance for pharmaceutical and cosmetic industry. The study was conducted in the period 2007–2009 on loess soil with the granulometric composition of silt loam. The aim of the experiment was to determine the effect of different nitrogen doses (0, 40, 80,...