The records of 403 patients treated for herniated lumbar disc disease were analysed in a retrospective observational study in order to verify how three outcome measures, i.e., satisfaction with the outcome of surgery, the degree of return to activities of daily living including work (ADL), and duration of interruption of ADL, may be influenced by clinical variables. Age, type of disc herniation...

Objective. The aim of this study was to evaluate the efficacy of a three-dimensional (3D) turbo spin-echo (TSE) sequence for determining lumbar disc protrusions, and to compare the findings with those of conventional two-dimensional (2D) TSE sequences and reveal the interobserver and intermethod agreements of both sequences. Methods. A total of 127 discs from 84 patients were evaluated by three...

A retrospective review of computed tomograms (CT) was performed in eight patients who underwent surgery for presumed reherniation of a lumbar disc. The CT scan in the three patients with surgically proven extradural scarring and no disc herniation, demonstrated distinct characteristics of perineural fibrosis which differed markedly from the uniform changes seen on the scans of the five patients...

STUDY DESIGN A depression screener was used to determine positive responses amongst patients with two disorders commonly treated with surgery. OBJECTIVE To examine the relation between positive responses to the depression screener and pain characteristics, sociodemographic responses, and Short-Form 36-Item Health Survey subscale scores among patients with lumbar disc herniation or spinal sten...

PURPOSE Herniated nucleus pulposus fragments are recognized by the immune system as a foreign-body, which results in an autoimmune reaction. Human activation-inducible tumor necrosis factor receptor (AITR) and its ligand, AITRL, are important costimulatory molecules in the pathogenesis of autoimmune diseases. Despite the importance of these costimulatory molecules in autoimmune disease, their r...

BACKGROUND Open discectomy is the standard surgical procedure in the treatment of patients with long-lasting sciatica caused by lumbar disc herniation. Minimally invasive approaches such as microendoscopic discectomy have gained attention in recent years. Reduced tissue trauma allows early ambulation, short hospital stay and quick resumption of daily activities. A comparative cost-effectiveness...

STUDY DESIGN The serum levels of transforming growth factor-beta 1 (TGF-beta1), tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) and TIMP-2 were measured by enzyme-linked immunosorbent assay. PURPOSE To compare the serum levels of TGF-beta1, TIMP-1 and TIMP-2 between patients with lumbar spinal stenosis and disc herniation. OVERVIEW OF LITERATURE It has been reported that increased c...

A twelve year old boy presented with acute cervical and interscapular pain, torticollis and low grade fever. The neurological examination was normal. Roentgenograms showed calcification of the T3-T4 disc and posterior herniation of the nucleus pulposus was demonstrated by computed tomography. A rapid and dramatic amelioration of the symptoms was produced by treatment with a non-steroidal anti-i...

Clinical and Morphological Findings of Disc Herniation by use Different MRI Sequences Observers

BACKGROUND The usual surgical treatment of refractory sciatica caused by lumbar disc herniation, is open discectomy. Minimally invasive procedures, including percutaneous therapies under local anesthesia, are increasingly gaining attention. One of these treatments is Percutaneous Laser Disc Decompression (PLDD). This treatment can be carried out in an outpatient setting and swift recovery and r...