نتایج جستجو برای: caffeic acid derivatives

تعداد نتایج: 834920  

Journal: :Carcinogenesis 2006
Won Jun Lee Bao Ting Zhu

We studied the modulating effects of caffeic acid and chlorogenic acid (two common coffee polyphenols) on the in vitro methylation of synthetic DNA substrates and also on the methylation status of the promoter region of a representative gene in two human cancer cells lines. Under conditions that were suitable for the in vitro enzymatic methylation of DNA and dietary catechols, we found that the...

2015
Lucia Natarelli Giulia Ranaldi Guido Leoni Marianna Roselli Barbara Guantario Raffaella Comitato Roberto Ambra Francesco Cimino Antonio Speciale Fabio Virgili Raffaella Canali Shilpa J Buch

Epidemiological studies suggest that moderate and prolonged consumption of coffee is associated with a reduced risk of developing type 2 diabetes but the molecular mechanisms underlying this effect are not known. In this study, we report the effects of physiological concentrations of caffeic acid, easily achievable by normal dietary habits, in endothelial cells cultured in 25 mM of glucose (hig...

Journal: :Biological & pharmaceutical bulletin 2009
Kwan Hee Park Min Park Sun Eun Choi Mi Sook Jeong Joo Hee Kwon Myung Hwan Oh Hyung Kyun Choi Seong Jun Seo Min Won Lee

Activity guided fractionation of Aconitum koreanum root extract (RAK), a traditional medicine in Korea, afforded four caffeoyl derivatives, caffeic acid (1), 4,5-dicaffeoylquinic acid (2), 3,5-dicaffeoylquinic acid (3) and 3,5-dicaffeoylquinic acid methyl ester (4). In order to evaluate the anti-oxidative and anti-inflammatory effects of these compounds, their 1,1-diphenyl-2-picrylhydrazyl (DPP...

Journal: :The Biochemical journal 2002
Hideo Iwahashi Koji Nishizaki Ichiro Takagi

A reaction of 13-hydroperoxide octadecadienoic acid (13-HPODE) with cytochrome c was analysed using ESR, HPLC-ESR and HPLC-ESR-MS by the combined use of the spin-trapping technique. The ESR, HPLC-ESR and HPLC-ESR-MS analyses showed that cytochrome c catalyses formation of pentyl and octanoic acid radicals from 13-HPODE. On the other hand, only the alpha-(4-pyridyl-1-oxide)-N-t-butylnitrone/octa...

Journal: :Food chemistry 2012
Céline Chanforan Michèle Loonis Nathalie Mora Catherine Caris-Veyrat Claire Dufour

The effect of industrial processing was investigated on the stability of tomato carotenoids, phenolic compounds and ascorbic acid. A deep insight in the processed products allowed the quantification of caffeic acid hexosides, which are far more important contributors than the well-known chlorogenic acid, dicaffeoylquinic acids and quercetin oligosaccharides (new feruloyl, sinapoyl and syringoyl...

Journal: :iranian journal of pharmaceutical sciences 0
yaghoub amanzadeh department of pharmacognosy mahnaz khanavi department of pharmacognosy mahboube khatamsaz department of pharmacognosy afsaneh rajabi department of pharmacognosy seyed esmaeil sadat ebrahimi department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran

eight samples of flowering tops from six species of the genus crataegus l., commonly called hawthorn, from different geographic locations of iran were standardized according to german pharmacopoeia monograph on crataegi folium cum flore (hawthorn leaf with flower) by high-performance thin-layer chromatograph-ic (hptlc) fingerprinting combining with digital scanning profiling of their major poly...

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