Neurotransmission at chemical synapses involves regulated exocytosis of neurotransmitter from the presynaptic terminal. Neurotransmitter release is thought to be triggered by calcium influx through specific classes of voltage-gated calcium channels. Here we report genetic and functional analysis implicating a specific calcium channel gene product in neurotransmitter release. We have isolated a ...

Biomaterials have evolved over the past three decades and are relatively specialized, highly biocompatible, but low-strength dental materials. Bioactive materials can interact with living tissues or systems. The newly emerging bioactive category of has expanded clinical uses in restorative dentistry endodontics. Examples Calcium Silicate containing Mineral Trioxide Aggregate (Portland cement); ...

BACKGROUND The use of oral calcium supplementation among the elderly for prevention and treatment of osteoporosis and osteopenia is increasing. The incidence of aortic valve disease and coronary artery disease also is increasing. No study thus far has been done to demonstrate whether this affects the progression of calcification in both the valves and vasculature. We sought to determine whether...

Tartaric acid (TA) changes short-term mechanical behavior and phase composition of sodium-metasilicate activated calcium-aluminate cement blend with fly ash, type F, when used as a set control additive to allow sufficient pumping time for underground well placement. The present work focuses on TA effect on self-healing properties of the blend under steam or alkali carbonate environments at 270 ...

Background/Overview CORONARY ARTERY CALCIUM Coronary artery calcium (CAC) is associated with coronary artery disease (CAD) based anatomic studies. The development of fast CT scanners has allowed the measurement of CAC in clinical practice. CAC has been evaluated in several clinical settings. The most widely studied indication is for the use of CAC in the prediction of future risk of CAD in pati...

Fly ash belite cement is a green, low carbon cementitious material, mainly composed of hydraulic minerals dicalcium silicate and calcium aluminate. In this study, we used fly to control the setting time, hydration heat, strength, composition microstructure products in Portland cement. Results showed that incorporating into can shorten accelerate reaction speed, enhance early heat release rate r...

Ye’elimite is a dominant phase in calcium sulfoaluminate cement, which promising alternative type of cementitious binder. Ca3.8Na0.2Al5.6Fe0.2Si0.2SO16 (abbreviated as ss-C4A3$) kind typical doped solid-solution ye’elimite. In this study, the formation process ss-C4A3$ was investigated. Clinkers were sintered at various temperatures for different holding times. X-ray diffraction tests and Rietv...

PURPOSE To investigate the association between aortic root calcification (ARC) and coronary artery calcification (CAC) assessed by coronary artery calcium-scoring dual-source computed tomography (DSCT). MATERIALS AND METHODS We retrospectively analyzed 143 consecutive patients who underwent coronary artery calcium-scoring during coronary DSCT angiography. 57 patients had findings of ARC on ca...