idiopathic cd4+ lymphocytopenia is a rare combined immunodeficiency disease, characterized by low cd4+ t-cell count and increased susceptibility to opportunistic infections, autoimmunity and malignancies after exclusion of secondary forms of cd4 lymphocytopenia. here we present a 13-year old boy who was referred to our center because of destructive ulceration of soft and hard palates with exten...

the occurrence of langerhans cell histiocytosis (lch) in a patient with lymphoma is an indication of a probable relationship between them. the two conditions have similarities both clinically and histopathologically. occurrence of these two conditions in the same patient, particularly not simultaneously, is rare. according to different management and treatment of these conditions, exact histopa...

a 34-year-old hiv positive-man was admitted to the hospital due to fever and abdominal pain. constant and generalized abdominal pain started 3 months prior to admission (pta) in upper quadrants of abdomen followed by mild odynophagia, early satiety and more than 20 kg weight loss since then. intermittent fever begun 7 days pta and cough, sputum and dyspnea started since 5 days pta. his general ...

Primary cutaneous large B-cell lymphoma leg type is a rare andaggressive neoplasm as defined by the recently updated WorldHealth Organization - European Organization for Research andTreatment of Cancer. We report a case of an 80-year-old manwith multiple cutaneous lesions. Here, we review the availableliterature and summarize clinical features and management ofthis type of cutaneous B-cell lymp...

peripheral t-cell lymphomas are a group of heterogeneous disorders and according to who classification, are categorized into nodal and extranodal forms. nk/t-cell lymphoma, nasal type, is a subtype of extranodal peripheral t-cell lymphoma and commonly presents as a midfacial destructive lesion. this disorder is more prevalent in asia and south america and has a strong association with epstein b...

Introduction: Lymphoma is a common malignant tumor of the head and neck occurring during childhood. Early diagnosis is very important in terms of prognosis in patients with tonsillar lymphoma.Our objective was to evaluate the clinical manifestations of pediatric tonsillar lymphoma according to different age groups.  Materials and Methods: A systematic review of available English, Spanish, or Po...

Extranodal natural killer cell (NK) T lymphoma (ENKL) is a rare type of non Hodgkins lymphoma, accounting for 5% 10% total NHL cases.

: Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of non-Hodgkin's (NHL), characterized by poor outcome, accounting approximately for 10%-15% all non-Hodgkin in the western countries, and with higher prevalence Asia. Cyclin D1 immunoreactivity is characteristically seen mantle cell lymphoma. It also observed hairy leukemia, plasma myeloma proportion diffuse large B-cell lymp...

lymphomas are solid malignant tumors having a wide spectrum of clinical and pathological features. non-hodgkin’s lymphoma (nhl) is a subtype of lymphoma with two-thirds of the cases presenting as lymph node enlargement. the remaining one third of nhl cases has been reported in the extranodal sites, including the gastro intestinal tract, waldeyer’s ring, bone, skin, and brain. intraoral non-hodg...