One of the imperative features of the oral cavity is the presence of different areas, which are characterized by unique sets of tissue organization. These regions are divided into lining mucosa (buccal mucosa, labial mucosa, alveolar mucosa, mucosa lining the ventral surface of the tongue, floor of the mouth, and soft palate) and masticatory mucosa (hard palate, attached gingiva, and dorsal sur...

Dear Editor, I was very pleased to find that the article” Micronucleus Assay of Buccal Mucosa Cells in Waterpipe (Hookah) Smokers: A Cytologic Study “(1) has attracted the attention of some readers and has created a few points for them. In my opinion, these points are good bases to overcome some concerns regarding micronucleus assay.

Buccal delivery of saquinavir has the advantage to bypass hepatic first-pass metabolism associated with oral administration. Local microenvironmental pH (pHM) modification at buccal mucosa might increase absorption by balancing solubility and partition into mucosa. The present study aimed evaluate a novel pHM modifying film using effervescence, as well elucidate relationship between permeation ...