Ankur Gulati, MD*; Tevfik F. Ismail, MD*†; Andrew Jabbour, MD, PhD*; Francisco Alpendurada, MD*; Kaushik Guha, MD*†; Nizar A. Ismail, BSc*; Sadaf Raza, MD*; Jahanzaib Khwaja, BSc*; Tristan D.H. Brown, BSc*; Kishen Morarji, MD*; Emmanouil Liodakis, MD*; Michael Roughton, MSc*; Ricardo Wage, DCR*; Tapesh C. Pakrashi, MD*; Rakesh Sharma, MD, PhD*†; John-Paul Carpenter, MD*†, Stuart A. Cook, MD*†; ...

Semantic tagging of images has a broad spectrum of applications, of both scientific and commercial interest. Experience has indicated that designing the interaction with human taggers in the form of a web game can be a very effective way to collect valuable tagged data. So far, implementations of such games have depended on explicit, deliberate input by the users. A novel alternative is present...

Nicola Whiffin, PhD, Roddy Walsh, MSc, Risha Govind, MSc, Matthew Edwards, MSc, Mian Ahmad, PhD, Xiaolei Zhang, MSc, Upasana Tayal, BMBCh, MRCP, Rachel Buchan, MSc, William Midwinter, BSc, Alicja E Wilk, BSc, Hanna Najgebauer, PhD, Catherine Francis, MA, MRCP, Sam Wilkinson, BSc, Thomas Monk, MSc, Laura Brett, MPhil, Declan P O’Regan, PhD, FRCR, Sanjay K Prasad, MD, FRCP, Deborah J Morris-Rosen...

BACKGROUND Cervical dystonia (CD) involves painful involuntary contraction of the neck and shoulder muscles and abnormal posture in middle-aged adults. Botulinum neurotoxin type A (BoNT-A) is effective in treating CD but little is known about its associated cost-effectiveness. OBJECTIVE To evaluate the cost-effectiveness of abobotulinumtoxinA for treating CD from the UK payer perspective. M...

Vital decisions made at the strategic level in an organization are not only intricate but also costly to alter. It is therefore important to find a comprehensive approach to deal with such a possibility. One of the major problems of a common balanced scorecard (BSC)-based model in strategic management is lack of a ranking system for strategic objectives in order to enable prioritization of the ...

M. Odumenya, BSc, MBBS, MRCS, Orthopaedic Registrar M. L. Costa, PhD, FRCS(Trauma and Orth), Associate Professor of Trauma and Orthopaedics Surgery N. Parsons, BSc, MSc, PhD, Medical Statistician J. Achten, MSc, PhD, Research Manager Clinical Sciences Research Institute M. Dhillon, FRCR, Consultant Radiologist S. J. Krikler, BSc, PhD, FRCS(Ortho), Consultant Orthopaedic Surgeon University Hospi...

N Ferreira BSc, MBChB, HDip Orth(SA), FC Orth(SA), MMed(Orth) Tumour, Sepsis and Reconstruction Unit, Department of Orthopaedics, Grey’s Hospital, University of KwaZulu-Natal LC Marais MBChB, FCS Orth(SA), MMed(Ortho) Tumour, Sepsis and Reconstruction Unit, Department of Orthopaedics, Grey’s Hospital, University of KwaZulu-Natal C Aldous BSc, BSc(Hons), MSc, PhD Medical Research Scientist, Scho...

The non-invasive Xe inhalation method was modified to measure regional cerebral blood flow (rCBF) of both hemispheres and brain stem-cerebellar (BSC) regions in baboons to serve as a model for clarifying and validating human studies. Measurements were made in the alert, unanesthetized state at rest and during activation with spontaneous respiration in a primate chair or during sedation or anest...

Satellite cells are the resident stem cell population of adult skeletal muscle tissue that is responsible for growth and regeneration. The cells typically congregate near the tips of the muscle fi bers and in close proximity to the neural muscular junction (NMJ). Ephrin-A5 is a chemotactic molecule that participates in the correct positioning and formation of the NMJ. The objective of the exper...

BACKGROUND Current chemotherapy in platinum-resistant ovarian cancer patients has demonstrated minimal to no improvements in survival. Despite the lack of benefit, significant resources are utilized with such therapies. Therefore, the objective in the current study was to assess the cost-effectiveness of salvage chemotherapy for patients with platinum-resistant epithelial ovarian cancer (EOC). ...