Background: Nisin, an effective natural food preservative, is an antimicrobial peptide produced by Lactococcus lactis. Although it has been mainly studied and developed as a potential alternative for antibiotics, other pharmacological effects of the nisin including cytotoxic and anti-tumor activity have been attracted many attentions.Objectives: Here, we ...

Previous research has indicated that seasonal-type heat stress (HS) can contribute to the development of pale, soft, exudative (PSE) meat in fast-growing turkeys and that halothane exposure may identify stress-susceptible animals. This study evaluated the ability of halothane screening to identify stress-susceptible birds prone to developing pale, exudative meat when reared to market age. Two l...

A multistep synthesis was developed to prepare new 1,2,3-triazole-amino acid conjugates (6 and 7). These compounds contain the diaryl ether moiety were synthesized via SNAr reaction under mild condition in good yield. Their structures confirmed by spectroscopic analyses (HR-MS, NMR, IR). showed significant antiproliferative activity (>30%) toward breast MCF7 liver HepG2 cancer cells lines at...

My research seeks to aid in developing approaches to prevent breast cancer. This research evolved from our early empirical studies for discovering natural compounds with anticancer activities, coupled with clinical evaluation to a genetics-driven approach to prevention. This centers on the use of comparative genomics to discover risk-modifying alleles that could help define population and indiv...

Mammography is currently the most effective noninvasive means of imaging the breast. Initially developed as a diagnostic aid to evaluate clinically detected breast abnormalities, mammography has evolved to be a widely used method to screen occult breast cancers in asymptomatic women. During the past 20 years, there has been substantial advancement in this field, in terms of image quality and re...

BACKGROUND/AIM The role of retinoid X receptor alpha (RXRα) and peroxisome proliferator-activated receptor gamma (PPARγ) in breast cancer has been well studied in vitro. The aim of the study was to assess the presence of these molecules in human breast cancer specimens and correlate them with major clinicopathological features. PATIENTS AND METHODS Tissue sections from 82 breast cancer cases ...

Objective: This study aimed to determine phenotypic correlations between carcass part yields (breast and thigh yield) meat quality characteristics (pHu, lightness, redness, yellowness, chroma, hue, thawing loss, cooking water holding capacity, texture) in Japanese quails.Material Methods: was carried out on a total of 130 quails with mixed sexes. Twenty-four hours after slaughter, pHu color mea...

Filtered back-projection (FBP) has been commonly used as an efficient and robust reconstruction technique in tomographic X-ray imaging during the last decades. For limited angle tomography acquisitions such as digital breast tomosynthesis, however, standard FBP reconstruction algorithms provide poor results and give rise to image artifacts due to the limited angular range and the coarse angular...