BACKGROUND We aimed to quantitatively assess the effect of baseline breast density on the incidence, stage, and mortality, and also the natural course of the disease, considering the sensitivity of mammography to clarify its causal or masking effect. METHODS In total, 15,658 women ages 45 to 59 years from the Kopparberg randomized controlled trial in Sweden were prospectively followed from 19...

Normal human breast tissue consists of epithelial and nonepithelial cells with different molecular profiles and differentiation grades. This molecular heterogeneity is known to yield abnormal clones that may contribute to the development of breast carcinomas. Stem cells that are found in developing and mature breast tissue are either positive or negative for cytokeratin 19 depending on their su...

Axillary masses have diverse origins and require systematic diagnosis treatment. Among various diseases, ectopic breast tissue occurs when the regression of primitive mammary fails in a location other than pectoral breast. Ectopic was significantly rarer men, accounting for 5.3% all cases. We report case 57-year-old male patient who presented with large axillary mass. Surgical excision patholog...

BACKGROUND Caveolin-1 is thought to have an important impact on both signal transduction and mediation of intracellular processes. Furthermore, it has been suggested that Caveolin-1 may contribute to certain steps of carcinogenesis in various types of cancer. We examined the potential clinical relevance of Caveolin-1 in normal, benign and malignant breast tissue specimens. METHODS Using tissu...

OBJECTIVES There is a paucity of data on cyclooxygenase (COX)-2 expression in normal breast tissue and on the changes in COX-2 expression from normal tissue via ductal carcinoma in situ (DCIS) lesions to invasive cancer. The aim of this study, therefore, was to investigate COX-2 protein expression in normal breast tissue, DCIS, and invasive breast cancer in samples from the same patients. MET...

In cases with breast cancer, probably benign lesions can also be seen in the other areas of breast. It is known that neoadjuvant chemotherapy causes morphological changes normal tissue and lesions, addition to effects on malignant mass. complete response chemotherapy, without diagnosis cause a dilemma conserving surgery plan, when they shrink or disappear at end treatment. We aimed demonstrate ...

Breast emergencies are not frequent but play an important part in routine breast imaging applications. Diagnosis and identification of seat belt injury emergency department essential for patient management early treatment advanced cases. Herein we reported findings a who had prominent swollen at her left accompanying tissue edema painful palpable mass formed by active bleeding hematoma as resul...

Breast cancer is the most common killer in women worldwide, which is originating from breast tissue. Early detection of breast cancer plays an important role in its therapy. Existing breast cancer detection method like ultrasound imaging can not be used at all ages, also quality of obtained images affected by speckle noise. Thus, it is essential to introduce new method to overcome these problem...