breast conservation surgery combined with radiation therapy is now an accepted option for the treatment of early breast cancer. so we decided to evaluate the results of such treatment in our first group of patients treated by this method. from 1992 to 1996 , one hundred patients with stage i and ii breast cancer treated with breast conservative surgery (lumpectomy or quadrantectomy). were irrad...

background : stage at diagnosis is one of the most important prognostic factors for most of the cancers like breast cancer. studies have found that the rate of late-stage diagnosis of breast cancer among women with lower socioeconomic status is more than the others. the aim of this study was investigating the relationship between family levels of socioeconomic status and stage at diagnosis of b...

background: a soluble form of her-2/neu extracellular domain (sher-2) is reported to be released in the sera of metastatic breast cancer patients. objective: to measure the level of sher-2 in sera of 115 breast cancer patients. methods: serial samples of 27 patients with metastasis, 18 non-metastatic patients, 15 patients in stage 0/i and 14 patients with accompanying benign breast disease were...

Objective(s):Cytochrome P-450 1A1 is an important enzyme in the first phase of the metabolism of some carcinogens such as polycyclic aromatic hydrocarbons (PAHs), as well as estrogen. The present study evaluates the existence of CYP1A1 polymorphism in a number of breast cancer samples. Materials and Methods: One hundred breast cancer patients and the same number of healthy controls were analyz...

conclusions when compared to the control group, the swedish massage showed an improvement in the mood disorders of women with breast cancer. results before the intervention, there was no significant difference in the average of the overall scale between the intervention and control groups in the subscales of anger, anxiety, depression, and positive affect (p = 0.469). the average of the overall...

Background: Cancer stem cells (CSCs) are a group of tumor cells with self-renewal property and differentiation potential. CSCs play a crucial role in malignant progression of several types of tumors. However, what is still controversial is the clinicopathological relationship between Nanog marker and its prognostic value in the patients with breast cancer. The expression of Nanog in the patient...

patients and methods in this cross-sectional study, data of 584 female patients (mean age of 45.9 years) referred to breast cancer research center (tehran, iran) were analyzed anonymously. spss and norm softwares (2.03) were used for data transformation, running and interpretation of cca and replacing missing values, respectively. data were obtained from breast cancer research center, tehran, i...

background: this study intends to determine the diagnostic and prognostic roles of hypermethylation of serum rassf1a and protocadherin-10 promoters in females with breast cancer. methods: this study enrolled 80 breast cancer patients and 80 apparently normal healthy controls. the promoter methylation status of serum rassf1a and pcdh10 genes was investigated using methylation specific pcr. resul...