benzofuran as an important heterocyclic compound is extensively found in natural products as well as synthetic materials. since benzofuran drivatives display a diverse array of pharmacological activities, an interest in developing new biologically active agents from benzofuran is still under consideration. this review highlights recent findings on biological activities of benzofuran derivatives...

breast cancer (bc) is considered as one of the most important causes of death worldwide. previous studies showed that apolipoprotein b mrna- editing catalytic polypeptide-like 3 (apobec3) gene deletion significantly increased the risk of bc risk in chinese and european women. the present study aimed to assess the possible impact of apobec3 deletion and the risk of bc in a sample of iranian popu...

background: this study aims to demonstrate the frequency of malignant breast cancer (bc) according to pathologic findings in birjand during 2011-2013 years. methods: for this cross-sectional study, the sample consisted of pathologic records from 229 breast biopsies of two hospitals in birjand. results: most of the biopsies in women were malignant cases which nearly 90% of them were detected aft...

granymeh is a functional cytotoxic serine protease of nk cell granules,which expands the cell death-inducing repertoire of innate immune system.the purpose of this study was to determine granymeh(gzmh)level in breast cancer(bc) and healty women.this study was performed on 30 patients with bc and 30 healty woman.gzmh and estrogen levels were measured in cancer patients  and healty women subseque...

background: one of the economic evaluation techniques involves calculation of willingness to pay (wtp) for a service to find out the value of that service from the clients’ perspective. this study estimated wtp for both breast cancer and osteoporosis screening and comparatively examined the contributing factors. in fact, the comparisons served to provide an exact analysis of individual attitude...

objective(s): this study addresses feature selection for breast cancer diagnosis. the present process uses a wrapper approach using ga-based on feature selection and ps-classifier. the results of experiment show that the proposed model is comparable to the other models on wisconsin breast cancer datasets. materials and methods: to evaluate effectiveness of proposed feature selection method, we ...

adiponectin is one of the most important members of adipokine family which is widely synthesized and secreted by adipose tissue. the action of adiponectin is via binding to main receptors. it has several actions including regulation of glucose level, lipid homeo­stasis and reproductive system. adiponectin can also influence vascular endothelium via preventing the migration of monocytes. the rol...

nipple discharge (nd) can be the earliest presenting symptom of breast cancer. we hereby present two cases of breast cancer with no palpable mass manifesting as isolated nd, which was whitish in color. in both cases, cytology of the discharge revealed highly pleomorphic cells indicating a high grade malignancy. mammography showed diffuse, extensive microcalcifications. simple mastectomy with ax...

background: cylindroma of the breast is a rarely described tumor that closely resembles its dermal counterpart. case presentation: we report a case of a 55-year-old woman with an incidental finding of a left breast mass on screening mammography. on histologic examination, the tumor was found to be consistent with cylindroma of the breast. conclusion: generally considered to be a benign lesion, ...

introduction in recent years methods based on radio frequency waves have been used for detecting breast cancer. using theses waves leads to better results in early detection of breast cancer comparing with conventional mammography which has been used during several years. materials and methods in this paper, a new method is introduced for detection of backscattered signals which are received by...