نتایج جستجو برای: brain white matter hyperintensities

تعداد نتایج: 816747  

2002
J M Starr J Deary L J Whalley

Objective: To investigate the relations between premorbid and current mental ability, mood, and white matter signal abnormalities detected by T2 weighted brain magnetic resonance imaging (MRI) and impairment of balance and mobility in older adults. Methods: 97 subjects from the Aberdeen 1921 birth cohort underwent brain MRI, evaluation of balance, and measurement of gait speed. White matter hyp...

Journal: :Journal of the American Heart Association 2015

Journal: :Journal of the American Geriatrics Society 2017

Journal: :NeuroImage 2010
S. Burgmans Martin P. J. van Boxtel E. H. B. M. Gronenschild E. F. P. M. Vuurman P. Hofman H. B. M. Uylings Jelle Jolles Naftali Raz

We investigated differences associated with age and hypertension, a common risk factor for vascular disease, in three aspects of white matter integrity--gross regional volumes of the white matter, volume of the white matter hyperintensities (WMH) and diffusion properties. We acquired MRI scans on 93 adult volunteers (age 50-77 years; 36 with diagnosis of hypertension or elevated blood pressure)...

Journal: :AJNR. American journal of neuroradiology 1990
D J Loes J Biller W T Yuh M N Hart J C Godersky H P Adams S P Keefauver D Tranel

We report four cases of biopsy proved cerebral amyloid angiopathy demonstrated by MR imaging. White matter signal hyperintensities on T2-weighted spin-echo pulse sequences were present in three patients. We believe the white matter lesions associated with cerebral amyloid angiopathy are not specific to this disorder but rather reflect hypoperfusion of distal white matter resulting from vascular...

Journal: :Archives of general psychiatry 2002
Alan J Thomas John T O'Brien Sue Davis Clive Ballard Robert Barber Rajesh N Kalaria Robert H Perry

BACKGROUND White matter hyperintensities on magnetic resonance imaging are increased in major depression in the deep white matter, especially in frontal areas. These lesions have been hypothesized to be ischemic in origin, but there have been no previous neuropathological studies in depression. We investigated the neuropathological basis of these lesions in depression, hypothesizing that they w...

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