As fluorine-18-fluorodesoxyglucose positron emission tomography/computed tomography ( (18)F-FDG PET/CT) is gaining wider availability, more and more patients with malignancies undergo whole body PET/CT, mostly to assess tumor spread in the rest of the body, but not in the brain. Brain is a common site of metastatic spread in patients with solid extracranial tumors. Gold standard in the diagnosi...

PURPOSE Dynamic contrast-enhanced T2*-weighted MR imaging has been helpful in characterizing intracranial mass lesions by providing information on vascularity. Tumefactive demyelinating lesions (TDLs) can mimic intracranial neoplasms on conventional MR images, can be difficult to diagnose, and often result in surgical biopsy for suspected tumor. The purpose of this study was to determine whethe...

Glial tumours, in particular those of astrocytic origin, are the most common primary brain tumours and account for more than 40% of all central nervous system (CNS) neoplasms (1). All neoplasms have an inherent tendency to progress towards a less differentiated, more malignant phenotype: this change reflects the sequential and cumulative acquisition of genetic alterations (2). Their incidence a...

We demonstrate the use of triple quantum (TQ) filtered sodium MRI in a group of patients undergoing clinical evaluation for primary brain tumors. The TQ images were acquired using a twisted-projection readout in tandem with a three-pulse triple quantum filter. Our results demonstrate that TQ sodium MRI provides a source of contrast that it is not biased by the large sodium content of the extrac...

BACKGROUND Although, substantial experimental evidence related to diagnosis and treatment of pediatric central nervous system (CNS) neoplasms have been demonstrated, the understanding of the etiology and pathogenesis of the disease remains scarce. Recent microRNA (miRNA)-based research reveals the involvement of miRNAs in various aspects of CNS development and proposes that they might compose k...

There are multiple non-neoplastic lesions that can mimic intracranial neoplasms on neuroimaging. The differentiation between neoplasms and these tumour-like lesions is essential to making the correct management decisions, not least because there is significant morbidity and mortality associated with brain biopsy and surgery. It is important for us as radiologists to be aware of these conditions...

Most epidemiology reports indicate that brain tumor rates in whites are higher than other populations and that they are more common in males than females. In this report, we analyze incidence patterns in registry data from the Surveillance, Epidemiology, and End Results program in different histological groups, racial/gender combinations and compare the overall and age-specific incidence rates....

Second lymphoid neoplasms are an uncommon but recognized feature of non-Hodgkin's lymphomas, putatively arising secondary to common genetic or environmental risk factors. Previous limited evaluations of clonal relatedness between successive mature B-cell malignancies have yielded mixed results. We describe the case of a man with intravascular large B-cell lymphoma involving the central nervous ...

This study aims at evaluating the application of magnetic resonance spectroscopy (MRS) in the differential diagnosis of brain tumors and inflammatory brain lesions. The examinations of 81 individuals, who performed brain MRS and were retrospectively analyzed. The patients with ages between 10 and 80 years old, were divided into two groups. Group A consisted of 42 individuals with diagnoses of c...