Intracranial metastases from carcinoma are common , occurring in up to 24% of cancer patients at autopsy [1]. Typically, intracranial metastatic disease is characterized by multiple intracerebral mass lesions near the gray-white junction with surrounding edema. Diffuse involvement of the brain without dominant mass lesions may occur with leptomeningeal spread of primary brain tumors, Iymphoprol...

Several patterns of brain allometry previously observed in mammals have been found to hold for sharks and related taxa (chondrichthyans) as well. In each clade, the relative size of brain parts, with the notable exception of the olfactory bulbs, is highly predictable from the total brain size. Compared with total brain mass, each part scales with a characteristic slope, which is highest for the...

Abstract Behavioural public policy is increasingly interested in scaling-up experimental insights to deliver systemic changes. Recent evidence shows some forms of individual behaviour change, such as nudging, are limited scale. We argue that we can scale-up change by accounting for nuanced social complexities which human responses behavioural policies situated. introduce the idea ‘social brain’...

background: angiotensin ii (ang ii) has an important role on cerebral microcirculation however, its direct roles in terms of ischemic brain edema need to be clarified. this study evaluated the role of central ang ii by using candesartan, as an at1 receptor blocker, in the brain edema formation and blood-brain barrier (bbb) disruption caused by ischemia/reperfusion (i/r) injuries in rat. methods...