نتایج جستجو برای: brain inflammation
تعداد نتایج: 633631 فیلتر نتایج به سال:
Post-ischemic inflammation is an essential step in the progression of brain ischemia-reperfusion injury. In this review, we focus on the post-ischemic inflammation triggered by infiltrating immune cells, macrophages, and T lymphocytes. Brain ischemia is a sterile organ, but injury-induced inflammation is mostly dependent on Toll-like receptor (TLR) 2 and TLR4. Some endogenous TLR ligands, high ...
Traumatic brain injury is one of the leading causes morbidity and mortality throughout world. Its increasing incidence, in addition to its fundamental role development neurodegenerative disease, proves especially concerning. Despite extensive preclinical clinical studies, researchers have yet identify a safe effective neuroprotective strategy. Following trauma, secondary from molecular, metabol...
n-3 and n-6 polyunsaturated fatty acids (PUFAs) are essential that provided by dietary intake. Growing evidence suggests PUFAs paramount for brain functions. They constitute crucial elements of cellular membranes, especially in the brain. precursors several metabolites with different effects on inflammation neuron outgrowth. Overall, long-chain accumulate offspring during embryonic post-natal p...
Impact of stress on diseases including gastrointestinal failure is well-known, but molecular mechanism is not understood. Here we show underlying molecular mechanism using EAE mice. Under stress conditions, EAE caused severe gastrointestinal failure with high-mortality. Mechanistically, autoreactive-pathogenic CD4+ T cells accumulated at specific vessels of boundary area of third-ventricle, tha...
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