نتایج جستجو برای: bortezomib microscopy ovariectomy rat stereology
تعداد نتایج: 470039 فیلتر نتایج به سال:
This study aims to explore the effects of exercise on postmenopausal osteoporosis and the mechanisms by which exercise affects bone remodeling. Sixty-three Wistar female rats were randomly divided into five groups: (1) control group, (2) sham-operated group, (3) OVX (Ovariectomy) group, (4) DES-OVX (Diethylstilbestrol-OVX) group, and (5) Ex-OVX (Exercise-OVX) group. The rat osteoporosis model w...
OBJECTIVE Raloxifene is a non-steroidal selective estrogen receptor modulator (SERM) that mimics estrogenic activity on bone density and blood lipid concentration without uterotropic actions. Previous data from our laboratory indicated that, as is the case for estrogen, neonatal administration of raloxifene disturbed normal differentiation of the hypothalamic circuitries governing the gonadotro...
Major advances in high-throughput, high-resolution, 3D microscopy techniques have enabled the acquisition of large volumes of neuroanatomical data at submicrometer resolution. One of the first such instruments producing whole-brain-scale data is the Knife-Edge Scanning Microscope (KESM), developed and hosted in the authors' lab. KESM has been used to section and image whole mouse brains at subm...
We consider selected geometric properties of 2D or 3D sets, given in form of binary digital pictures, and discuss their estimation. The properties examined are perimeter and area in 2D, and surface area and volume in 3D. We evaluate common estimators in stereology and digital geometry according to their multiprobe or multigrid convergence properties, and precision and efficiency of estimations....
This study aimed to evaluate the influence of estrogen deficiency and mechanical loading on bone around osseointegrated dental implants in a rat jaw model. The maxillary right first molars 36 rats were extracted. One week later, divided into an unloaded group loaded group; short head long inserted respectively. Nine weeks after implantation, further subjected ovariectomy (OVX) or sham surgery. ...
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