نتایج جستجو برای: boronic acid
تعداد نتایج: 747997 فیلتر نتایج به سال:
In general, benzothiazole derivatives have attracted great interest due to thier pharmaceutical and biological importance. New 2-amino-6-arylbenzothiazoles were synthesized in moderate to excellent yields via Suzuki cross coupling reactions using various aryl boronic acids and aryl boronic acid pinacol esters and the antiurease and nitric oxide (NO) scavenging activity of the products were also...
Synthesized thiolate boronic acid was found to complex with both a polysaccharide (dextran) and a monosaccharide (glucose) with similar affinities but displayed more affinity with dextran than with glucose when capped as a ligand on silver nanoparticle. Coupling on multiple sites of dextran, the silver particles were aggregated. The aggregated particles displayed a decrease of absorbance at 397...
Boronic acids bearing appropriate side chains are good inhibitors of serine amidohydrolases. The boron usually adopts a tetrahedral conformation, bound to the nucleophilic serine of the active site and mimicking the transition state of the enzymatic reaction. We have solved the structures of complexes of a penicillin-binding protein, the DD-peptidase from Actinomadura sp. R39, with four amidome...
The boronic acid derivatization of carbohydrates is demonstrated as an ion mobility shift strategy to improve confidence in the identification and characterization of carbohydrate assignments using ion mobility-mass spectrometry.
A new coordination polymer of polyoxomolybdate, {[Cu(4)(bbp)(5)Mo(6)O(22)]·(H(2)O)(4)}(∞) (bbp = 1,4-bis(benzoimidazol-1-yl)phenyl), has been synthesized under solvothermal reaction, which represents a double-bridging interpenetrating α-Po network based on the bimetallic cluster {Cu(4)Mo(6)}. The thermogravimetric and electrochemical behaviors have also been studied.
Back Cover: In article number 2100121, Suchetan Pal and co-workers develop a family of multi-responsive polymer hydrogels crosslinked with bis boronic acid molecules. Hydrogels tetrahydroxydiboron show glucoseresponsive degradation in the presence glucose oxidase (GOX) enzyme. Furthermore, insulin releases under high conditions physiological milieu.
Plasmonic nanostructures are intensely investigated as sensors due to their high sensitivity to changes in their nearest dielectric environment. However, additional steps have to be taken to provide specificity for a particular analyte. Here, gold nanoantennas are coated with a thin layer of a boronic acid functionalized hydrogel, which reversibly swells in the presence of glucose. This process...
Novel boron-containing drugs have recently been suggested as a new class of pharmaceuticals. However, the majority of current boron-detection techniques require expensive facilities and/or tedious pretreatment methods. Thus, to develop a novel and convenient detection method for boron-based pharmaceuticals, imine-type boron-chelating-ligands were previously synthesized for use in a fluorescent ...
We have tested the feasibility of tear glucose sensing using a daily, disposable contact lens embedded with boronic acid-containing fluorophores as a potential alternative to current invasive glucose-monitoring techniques. Our findings show that our approach may, indeed, be suitable for the continuous monitoring of tear glucose levels in the range 50-500 microM, which track blood glucose levels...
Boronic acid functionalized multi-walled carbon nanotubes (MWNTs) have been synthesized and used for sensitive dopamine (DA) detection using electrochemical methods in the presence of excess L-ascorbic acid (L-AA) via specific, reversible formation of a boronate ester between DA and the functionalized MWNTs.
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