PURPOSE The primary objective of this study was to analyze the relationships between bone microstructure and strength, and male osteoporosis risk factors including age, body mass index, serum 25-hydroxyvitamin D level, and testosterone level. A secondary objective was to compare microstructural and strength parameters between men with normal, low, and osteoporosis-range areal bone mineral densi...

Background: Hamstring tendons are secondary hip extensors. Their harvest for graft in anterior cruciate ligament(ACL) reconstruction may create deleterious effect on hip extension strength. This is of particular importance in sportsthat need powerful hip extension force like climbing and sprinting. Due to scarcity of a comprehensive study in thisarea, we designed this prospect...

Coefficients of correlation between certain physical properties and the histological components of the break area were calculated on an IBM 7090 computer for 56 femoral, 79 tibial and 37 fibular specimens of embalmed cortical bone of standardized size and shape. Strong positive correlations (0.01-0.02 significance level) were found between tensile strength and the percentage of interstitial lam...

A theoretical model for estimation of the bone-to-implant interfacial shear strength induced by implant surface roughness has been developed. Two different assumptions regarding the constitutive behaviour of the interfacial bone were made. 1) The bone exhibits an ideally plastic deformation – the plastic mode. 2) The bone exhibits a linearly elastic deformation – the elastic mode. In the plasti...

Objective Previous studies suggested that leptin has profound effects on bone metabolism and growth. Abnormal leptin and soluble leptin receptor (sOB-R) levels and their correlation patterns with bone mineral density and trabecular bone micro-architecture were recently found to be distinct in girls with adolescent idiopathic scoliosis (AIS). Structural Model Index (SMI) and data derived from Fi...

Bone disorders are of significant worry due to their increased prevalence in the median age. Scaffold-based bonetissue engineering holds great promise for the future of osseous defects therapies. Porous composite materials andfunctional coatings for metallic implants have been introduced in next generation of orthopedic medicine for tissueengineering. While osteoconductive materials such as hyd...

Although several studies have noted increased fracture risk in individuals with type 2 diabetes mellitus (T2DM), the pathophysiologic mechanisms underlying this association are not known. We hypothesize that insulin resistance (the key pathology in T2DM) negatively influences bone remodeling and leads to reduced bone strength. Data for this study came from 717 participants in the Biomarker Proj...

The design of the Farnsworth House is a fine illustration of the famous dictum, "less is more" by Mies van der Rohe. "I have no special talents, I am only passionately curious." summary / samenvatting summary / samenvatting summary / samenvatting summary / samenvatting summary Summary Summary Summary Summary Osteoporosis is a skeletal disorder that is fairly common among the elderly and particu...

Loosening is recognized as one of the primary sources of total hip replacement (THR) failure. In this study the influence of the bone surface texture on loosening of the cement/bone interface was studied. Model cemented hip replacements were prepared and subjected to cyclic loads that induced pure shear fatigue of the cement/bone interface. The femoral canals were textured with the use of speci...

Our goal in this cross-sectional study was to investigate the influence of low-vitamin D status on bone mass, bone turnover, and muscle strength in 301 healthy Chinese adolescent girls. Blood plasma 25-hydroxyvitamin D [25(OH)D] was measured by RIA and plasma and urine biomarkers of bone turnover were measured. Bone mineral content (BMC) and density and bone area for the whole body and the dist...