The new exposure of the Upper Muschelkalk clays and dolomites located south Kalety (Tarnogórski District, Silesia, Poland) provided numerous remains vertebrates represented by teeth, scales, long bones, coprolites. Despite influence hydrothermal processes leading to dolomitization Zn-Pb deposit formation, preservation fossil is good. taxonomic diversity accumulation vertebrate debris in dolomit...

The fundamental problem in osteoporotic fracture treatment is significant decrease in bone mass and bone tissue density resulting in decreased firmness and elasticity of osteoporotic bone. Application of standard implants and standard surgical techniques in osteoporotic bone fracture treatment makes it almost impossible to achieve stable osteosynthesis sufficient for early mobility, verticaliza...

We reviewed prospectively, after skeletal maturity, a series of 24 patients (25 hips) with severe acute-on-chronic slipped capital femoral epiphysis which had been treated by subcapital cuneiform osteotomy. Patients were followed up for a mean of 8 years, 3 months (2 years, 5 months to 16 years, 4 months). Bedrest with 'slings and springs' had been used for a mean of 22 days (19 to 35) in 22 pa...

Several years ago I was walking along a farm-road close to Piltdown Common, Fletching (Sussex), when I noticed that the road had been mended with some peculiar brown flints not usual in the district. On enquiry I was astonished to learn that they were dug from a gravel-bed on the farm, and shortly afterwards I visited the place where two labourers were at work digging the gravel for small repai...

Bone metastases ultimately result from a complex interaction between cancer cells and bone microenvironment. However, prior to the colonization of the bone, cancer cells must succeed through a series of steps that will allow them to detach from the primary tumor, enter into circulation, recognize and adhere to specific endothelium, and overcome dormancy. We now know that as important as the met...

Dental implant treatment is an excellent option for prosthetic restoration that is associated with high success rates. Implant stability is essential for a good outcome. The clinical assessment of osseointegration is based on mechanical stability rather than histological criteria, considering primary stability (absence of mobility in bone bed after implant insertion) and secondary stability (bo...

Upon physical examination, a well-delimited, 10-mm, hyperpigmented (dark brown) nodule, affecting the nail bed and hyponychium of the fifth right toe, was found ( fig. 1 ). Palpation evidenced hardened consistency. Upon physical examination of the entire body, the patient did not show any other lesions. The X-rays of the affected toe on its anterior-posterior and medium-lateral aspects did not ...

Mechanosensing is one of the crucial components of the biological events. In bone, as observed in unloading-induced osteoporosis in bed ridden patients, mechanical stress determines the levels of bone mass. Many molecules have been suggested to be involved in sensing mechanical stress in bone, while the full pathways for this event has not yet been identified. We examined the role of TRPV4 in u...

Camurati-Engelmann's syndrome is a rare congenital disease characterised by hyperostosis and sclerosis with a predilection for the long bones of the lower limbs. The authors report a case in an adult with a family history of the disease, and multiple localisations in the diaphyses of the long bones. The site of pain and greatest involvement of the disease was the right tibia and fibula. The aff...