The regulation of body weight and composition is complex, simultaneously affected by genetic architecture, the environment, and their interactions. We sought to analyze the complex phenotypic relationships between voluntary exercise, food consumption, and changes in body weight and composition and simultaneously localize quantitative trait loci (QTL) controlling these traits. A large (n = 815) ...

Introduction: Many indices are available to evaluate adiposity. A new index, body adiposity index (BAIp) (expressed in % fat) for children [Hip circumference (cm)/ Height (m)0.8) – 38] has been developed (El Aarbaoui et al., 2013). The objective of the present study was to use the index in a sample of preschool children to understand the association between BAIp and other anthropometric charact...

CONTEXT Elevated C-reactive protein (CRP) is a marker of cardiovascular risk in adults. Patterns and determinants of CRP in adolescents have not been well described. OBJECTIVE This study aimed to determine how CRP varies by age, gender, Tanner stage, and body fat composition in rural Chinese adolescents and to what degree adiposity-CRP associations are attributable to shared genetic and envir...

Age and adiposity can impact the digestibility of dietary proteins metabolic response to their ingestion. The objective was evaluate effects age on casein protein synthesis in tissues organs. Wistar rats 1 month (n = 15) 10 months at arrival were fed ad libitum with a standard diet or High Fat obtain normal high levels. Four groups constituted 7/8): 2 months/normal adiposity, months/high 11 adi...

BACKGROUND A determinant of blood pressure is adiposity; however, there are uncertainties surrounding whether general or central adiposity is the more important determinant of blood pressure. Further, inconsistent results exist for the relationships of anthropometric measures with blood pressure and hypertension, and whether these relationships differ substantially by age and sex is unclear. We...

Few studies have investigated the relationship between breakfast consumption and specific adiposity or insulin dynamics measures in children. The goal of this study is to determine whether breakfast consumption is associated with adiposity, specifically intra-abdominal adipose tissue (IAAT), and insulin dynamics in overweight Latino youth. Participants were a cross-sectional sample of 93 overwe...

The aim of this study was to examine diet quality among participants in the Atlantic Partnership for Tomorrow's Health (PATH) cohort and to assess the association with adiposity. Data were collected from participants (n = 23,768) aged 35-69 years that were residents of the Atlantic Canadian provinces. Both measured and self-reported data were used to examine adiposity (including body mass index...

The pattern of fat distribution is related to a large number of variables of clinical importance. Many anthropometric indices have been derived which are surrogate measures of central fat distribution. However, systematic information on age variations in regional adiposity and central fat distribution is incomplete. The present study investigates the age variations in regional adiposity and fiv...

OBJECTIVE Androgen excess in women is associated with visceral adiposity. However, little is known on the mechanism through which androgen promotes visceral fat accumulation. METHODS To address this issue, female mice to chronic androgen excess using 5α-dihydrotestosterone (DHT) and studied the regulation of energy homeostasis was exposed. RESULTS DHT induced a leptin failure to decrease bo...