Chemotactic responsiveness is crucial to neutrophil recruitment to sites of infection. During chemotaxis, highly divergent cytoskeletal programs are executed at the leading and trailing edge of motile neutrophils. The Rho family of small GTPases plays a critical role in cell migration, and recent work has focused on elucidating the specific roles played by Rac1, Rac2, Cdc42, and Rho during cell...

This study presents a dynamic-induced direct-shear model to investigate the dynamic triggering of frictional slip on simulated granular gouges. An incident P-wave is generated as a shear load and a normal stress is constantly applied on the gouge layer. The shear stress accumulates in the incident stage and the frictional slip occurs in the slip stage without the effect of the reflected wave. T...

This paper presents the development of a bioinspired flight control system and a characterization of its performance when operating in turbulent and gusting airflow conditions. This design consists of a skeletal structure with a network of feather-like panels installed on the upper and lower surfaces, extending beyond the trailing edge. Each feather is able to deform into and out of the boundar...

Patches of aggregated membrane proteins on motile fibroblasts are transported from the surfaces of the leading lamella to a site just ahead of the nucleus in the phenomenon known as capping. A major cell surface glycoprotein, Pgp-1 (GP80), was tagged with a monoclonal IgG and then aggregated with fluorescent secondary antibodies. Correlated digitized fluorescence and phase-contrast microscopy w...

The possibility of jet-installation noise reduction has been experimentally demonstrated using a flat-plate fitted with flow permeable metal foam at the trailing-edge. Tests were conducted for single-stream cold subsonic jets round nozzle adjacent to wide range velocities (M=0.3?0.9) in an anechoic chamber. Thorough investigations far-field various polar angles carried out demonstrate regions r...