Burned patients are at risk of acquiring infection because of their destroyed skin barrier, suppression of immunity, prolonged hospitalization, and invasive therapeutic and diagnostic procedures. Most of the studies on infections in burned patients are focused on burn wound infections, while nosocomial device-associated infections in this patient group are not described well. Therefore, the aim...

Blood transfusions remain common practice in the critical care and surgical settings. Transfusions carry significant risks, including risks for transmission of infectious agents and immune suppression. Transmission of bacterial infections, although rare, is the most common adverse event with transfusion. The risk for transmission of viral infections has decreased over time, clearly because test...

The distinction between causes of acute infections is a major clinical challenge. Current biomarkers, however, are not sufficiently accurate. Human neutrophil lipocalin (HNL) concentrations in serum or whole blood activated by formyl-methionine-leucine-phenylalanine (fMLP) were shown to distinguish acute infections of bacterial or viral cause with high accuracy. The aim was therefore to compare...

OBJECTIVE To test and validate a multiplex real-time polymerase chain reaction method for bloodstream infections, as well as to compare the results with conventional blood culture. METHODS A total of 114 consecutive patients with clinical evidence of sepsis were submitted to blood culture and LightCycler™ SeptiFast tests. RESULTS More positive specimens (23; 20.2%) were detected using the L...

occupational exposure to blood and body fluids is an important hazard for health care workers, which places them at a high risk for blood-borne infections including hepatitis b virus, hepatitis c virus and human immunodeficiency virus and results in psychological and emotional stresses. several preventive measures have been proposed including pre-exposure ( e.g. , education, use of standard pre...

Human Immunodeficiency Virus (HIV),Hepatitis B virus (HBV) and C virus (HCV) are known to be transmitted through blood and blood products. Many studies have been performed to determine relationship between infectious diseases and blood groups. This study aims to detect the relationship between the HIV, HBV and HCV infections with ABO and Rh D blood groups in Haryana. After blood donation, blood...

This paper discusses extracorporeal removal of viral particles and their antigens from the blood as an auxiliary therapy. This hypothesis has not been reported before. In some chronic blood-borne viral infections, the virus remains systemic and persistent for extended periods of time, with adverse effects that weaken the immune system. Blood titers of virus and its toxins are proportional to th...

Background. Transfusion-transmissible infectious agents such as human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV) and syphilis are among the greatest threats to blood safety for the recipient and pose a serious public health problem. The aim of this study was to determine the seroprevalence and risk factors for HIV, HBV, HCV and syphilis infections among blood...