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BACKGROUND Given the unpredictable timing of deceased donor organs and the need for blood transfusion, this study was carried out to determine the rate and risk factors for transfusion in order to identifying a low-risk cohort in the face of a critical blood shortage. METHODS This retrospective chart review examined 306 consecutive deceased solitary kidney transplant recipients from January 2...

One of the major challenges in developing programs for kidney transplantation is represented by presence antibodies targeting HLA donor recipients and, particular cases, incompatibility ABO blood groups among and recipient living donors [...]

BACKGROUND Optimal selection of blood donors is of paramount importance in ensuring the safety of blood products. The current selection process is concerned principally with the safety of the blood donor and the safety of the patient that receives the blood. Recent evidence suggests that the characteristics of the donor may affect transfusion outcomes for the recipient. METHODS We will conduc...

Background: Plasmapheresis is a well-recognised method for harvestingplasma.  It was introduced in the 1950s and is currently employed worldwide.  This method has been in use in Iran since 1979. Objective: To evaluate the efficacy of donor safety program used at the Iranian Blood Transfusion Organization. Methods: A comparison is made of the protein concentrations between the first-time and lon...

Transfusion of blood and its components/derivatives is a life saving medical intervention. However, this life saving procedure depends mainly on the availability of sufficient blood and its components in national health sector. Therefore the overall safety of transfusion medicines including the safety of blood and its available components and the appropriate use of these components would dir...

There is a significant risk of severe graft-versus-host disease (GVHD) and graft failure after unrelated umbilical cord blood transplantation (CBT) if donor-recipient pairs are mismatched at major histocompatibility complex (MHC) loci. To mitigate these risks after MHC-mismatched CBT, we infused psoralen-treated, photochemically inactivated, mature donor T-lymphocytes with MHC (H2-haplotype) mi...

BACKGROUND Despite the popularity of canine blood donor (BD) programs, there is scarce scientific information regarding iron status in this canine population of dogs. OBJECTIVE To assess iron status in dogs used in a blood donor program. ANIMALS A total of 130 healthy dogs (75 BD, 55 controls [C]) were included. A subset of dogs (n = 12) were used to evaluate the effects of repetitive donat...

BACKGROUND Blood availability is an issue of concern in countries of sub-Saharan Africa where both the demand and discard rates of blood are high. Although some degree of attention is paid when transfusion reactions occur in recipients, no information is available on donor reactions in this setting. OBJECTIVES This study was carried out in order to obtain some data on adverse reactions (ARs) ...