Amphiphilic rod-coil diblock copolymers consisting of flexible poly(ethylene oxide) (PEO) and rodlike poly{(+)-2,5-bis[4'-((S)-2-methylbutoxy)phenyl]styrene} (PMBPS) with predominant hydrophobic contents formed ordered monolayers at the air-water interface. The structures of monolayers transferred to a mica substrate at different surface pressures by the Langmuir-Blodgett method were investigat...

We report an extensive simulation study on the spontaneous formation of complex micelles from coilrod-coil amphiphilic triblock copolymers in dilute solution resulting from solvent selectivity. The amphiphilic molecule is built from one hydrophilic block on each side and a hydrophobic block in the middle. The rigidity of the rod block is introduced by adding a bond-bending potential of the angl...

We report the surface behavior andmorphologies of two series of pH-responsive amphiphilic heteroarm star block copolymers. In this respect, we studied polystyrene/poly(2-vinylpyridine)/poly(tertbutylacrylate), PSn(P2VP-PtBA)n, heteroarm star block terpolymers and their precursors, PSnP2VPn, star copolymers. These star block polymers differ in architecture (copolymer vs terpolymer), block topolo...

Two series of new electroactive and photoactive coil-rod-coil and rod-coil-rod triblock copolymers, poly (pentadecamethylene carboxester)-block poly(p-phenylene benzobisthiazole) block poly (pentadecamethylene carboxester) (1), and poly(2,6-benzoxazole)-Woc£poly(benzobisthiazole decamethylene)-WocÄ:-pory(2,6-benzoxazole) (2), were synthesized, characterized, and used to investigate the self-ass...

Peptide-decorated nanosystems have demonstrated higher stability and improved cellular uptake as compared to bare NPs appear highly promising in diagnostics theranostics of cancer. Herein, we discuss the preparation structural characterization peptide-functionalized silica/PEG NPs, starting from peptide–block copolymers, prepared turn by conjugation peptides block copolymers before NP formation...

Linear poly(VPGVG) has been extensively studied over the years as a model for the structural protein elastin. Elastin is characterized by a lower critical solution temperature (LCST). This LCST can be influenced by several factors, mainly molecular weight, concentration, and pH. An ABA type block copolymer was synthesized using atom transfer radical polymerization (ATRP), in which the VPGVG seq...

We report on a ternary isothermal system consisting of a poly(ethylene oxide)/poly(propylene oxide) (PEO/PPO) amphiphilic block copolymer, “water”, and “oil” (where “water” and “oil” are selective solvents for the different blocks), which exhibits the richest structural polymorphism ever observed (in equilibrium) inmixtures containing amphiphiles (such as block copolymers, surfactants, or lipid...

Microfluidic devices were developed that integrate the synthesis of well defined block copolymers and dynamic light scattering (DLS) measurement of their micelle formation. These metal devices were designed to operate in contact with organic solvents and elevated temperatures for long periods, and thus were capable of continuous in-channel atom transfer radical polymerization (ATRP) of styrene ...

Aqueous processing of globular protein-polymer diblock copolymers into solid-state materials and subsequent solvent annealing enables kinetic and thermodynamic control of nanostructure formation to produce block copolymer morphologies that maintain a high degree of protein fold and function. When model diblock copolymers composed of mCherry-b-poly(N-isopropylacrylamide) are used, orthogonal con...