Diagnosis and treatment of coagulation disorders associated with many veterinary diseases have been well studied, but the degree to which disorders of fibrinolysis may contribute to bleeding in veterinary patients is unknown. Recent data in the human and experimental literature suggests that the fibrinolytic pathway may be a useful target in patients with bleeding disorders and thrombotic disease.

severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. bone marrow aspiration (bma) is mandatory to differentiate from other blood diseases. an 8-year-old boy was admitted with recurrent epistaxis, pe...

Procedures in the field of head and neck surgery can be complicated by haemorrhage post-operative bleeding. Whilst it is commonplace to screen for coagulopathies pre-operative period, rare congenital bleeding disorders difficult detect have significant consequences. We report a case following routine sinus due an undiagnosed haemophilia A 65-year-old male.

Hemorrhagic diathesis can be caused by disorders in primary hemostasis (von Willebrand disease, inherited platelet function disorders), secondary hemostasis (hemophilia A, B, other coagulant factor deficiencies) and fibrinolysis, and in connective tissue or vascular formation. This review summarizes the approach to a bleeding patient starting from structured patient history, to applying bleedin...

Excessive bleeding after dental procedures are one of the most frequent complications occurring in patients with hereditary bleeding disorders. In this retrospective study we collected data from 10 years of experience in the oral care of patients with congenital haemorrhagic disorders in three Italian Hemophilia Centers. Between 1993 and 2003, 247 patients with inherited bleeding disorders unde...

The relation among the bleeding time, the peripheral venous hematocrit, and the amount of blood shed at the template bleeding time site has not been previously defined. We studied this relation in 227 persons: 26 were patients with idiopathic thrombocytopenic purpura (ITP), 137 were patients with a variety of other bleeding disorders, and 64 were healthy subjects. The bleeding time (mean +/- SD...