PROBLEM Blasting is a hazardous component of surface mining. Serious injuries and fatalities result from improper judgment or practice during rock blasting. This paper describes several fatal injury case studies, analyzes causative factors, and emphasizes preventive measures. METHOD This study examines publications by MSHA, USGS, and other authors. The primary source of information was MSHA's...

The assessment of fragmentation through blasting and therefore subsequent crushing and grinding stages is important in order to control and optimize the mining operation. Prediction of the mean size of fragmented rock by the rock mass characteristics, the blasting geometry, the technical parameters and the explosive properties is an important challenge for the blasting engineers. Some of the ef...

The use of blasting cost (BC) prediction to achieve optimal fragmentation is necessary in order to control the adverse consequences of blasting such as fly rock, ground vibration, and air blast in open-pit mines. In this research work, BC is predicted through collecting 146 blasting data from six limestone mines in Iran using the artificial neural networks (ANNs), gene expression programming (G...

ability to produce differentiated cell types and additional stem cells. Cells capable of proliferation and neurogen-*Division of Developmental Biology National Institute for Medical Research esis in such a paradigm, but which fail to self-renew, are best termed progenitor cells rather than stem cells. The Ridgeway, Mill Hill London NW7 1AA Detailed analyses demonstrating self-renewal have been ...

A mathematical model is used to investigate the effectiveness of the chemotherapy drug Topotecan against neuroblastoma. Optimal control theory is applied to minimize the tumor volume and the amount of drug utilized. The model incorporates a state constraint that requires the level of circulating neutrophils (white blood cells that form an integral part of the immune system) to remain above an a...

Surface cleaning processes are needed in different life cycle phases of technical products. They are important elements in manufacturing and in maintenance during usage as well as in recycling and remanufacturing. To meet the increasing requirements in product durability and functionality, the usage of compound materials and functional coatings becomes over more important. In this regard surfac...

Harry Mulisch, De ontdekking van de hemel.