We describe severe necrohemorrhagic cystitis in a female rhesus macaque and a female cynomolgus macaque due to colonization of the urinary bladder by Corynebacterium sp. Clinically, both macaques presented with perineal bleeding and depression and, despite extensive and prolonged treatment, succumbed to the disease. At necropsy, the contents of the urinary bladders in both cases were hemorrhagi...

Abstract Treatment goals in bladder pain syndrome (BPS) or interstitial cystitis (IC) focusing on relieving symptoms to improve quality of life and avoiding adverse events (AEs) since curative treatment for BPS/IC is not available. The readily available pharmacologic options including oral, intravesical, transdermal therapy. purpose this study review randomized trial studies over the last 15 ye...

BACKGROUND Interstitial cystitis/painful bladder syndrome (IC/PBS), is a severely debilitating chronic condition that is frequently unresponsive to conventional pain medications. The etiology is unknown, however evidence suggests that nervous system sensitization contributes to enhanced pain in IC/PBS. In particular, central nervous system plasticity of glutamatergic signaling involving NMDA an...

PURPOSE The purposes of this study were to investigate the effect of cyclophosphamide (CYP)-induced inflammatory cystitis on caveolin 1 in rat urinary bladder and to determine the role of these molecules in the bladder dysfunction that occurs in inflammatory change in rat urinary bladder. METHODS Female Sprague-Dawley rats were divided into control (n=30) and experimental (n=30) groups. Cysti...

Hemorrhagic cystitis is a disorder which causes bleeding from diffusely inflammatory bladder mucosa. Here we present a case of severe hemorrhagic cystitis caused by melphalan. A 70-year-old man with multiple myeloma was presented with suddenly commenced massive gross hematuria. During an attempt of transurethral coagulation of bladder mucosa, bladder perforation into peritoneal cavity was suspe...

www.trendsinmenshealth.com TRENDS IN UROLOGY & MEN’S HEALTH SEPTEMBER/OCTOBER 2017 Bladder pain syndrome (BPS), also referred to as interstitial cystitis (IC), is a chronic and debilitating condition. It presents with lower urinary tract symptoms in the form of urinary frequency, urgency, nocturia, and suprapubic and pelvic pain. The severity of the symptoms varies from person to person. It is ...

BACKGROUND Ketamine abuse has become a global phenomenon in recent years. Ketamine-induced cystitis (KC) is a new clinical syndrome which can result in severely inflamed bladder and intractable bladder pain. Currently there is no guideline for managing patients with KC. OBJECTIVES To analyze the clinical outcome of patients with KC managed with augmentation enterocystoplasty (AE). STUDY DES...

BACKGROUND Interstitial cystitis/painful bladder syndrome (IC/PBS) is a spectrum of pelvic, bladder or urethral pain, as well as irritative voiding symptoms. The term interstitial cystitis (IC) is reserved for patients with typical cystoscopic features. Diagnosis and management of this syndrome may be difficult. The aim of this study was to describe endoscopic features and our experience on the...

Background: Interstitial cystitis/painful bladder syndrome (IC/PBS), is a severely debilitating chronic condition that is frequently unresponsive to conventional pain medications. The etiology is unknown, however evidence suggests that nervous system sensitization contributes to enhanced pain in IC/PBS. In particular, central nervous system plasticity of glutamatergic signaling involving NMDA a...

Cystitis, necessitating the washing out of his bladder and draiuiug of his urine four times a day ; as this operation was attended with severe pain, I prescribed an injection of 1 ?/0 Cucaine, which allowed the catheter to be passed without pain or rigor until the original disease became somewhat cured, and the patient now passes the catheter himself, the great dread he had of the process havin...