to improve the accuracy of the activity quantification and the image quality in scintigraphy, scatter correction is a vital procedure. the aim of this study is to compare the accuracy in calculation of absorbed dose to patients following bone scan with 99m tc-marked diphosphonates ( 99m tc-mdp) by two different methods of background correction in conjugate view method. this study involved 22 pa...

BACKGROUND Fesoterodine is an antimuscarinic for the treatment of overactive bladder, a syndrome of urgency, with or without urgency urinary incontinence (UUI), usually with increased daytime frequency and nocturia. Our objective was to develop predictive models to describe the dose response of fesoterodine. METHODS Data from subjects enrolled in double-blind, placebo-controlled phase II and ...

abstract ureteralstump’s metastasis of renal cell carcinoma is rare. we report a32-year-old femalewith a huge metastatic involvement of the ureteralstump and utero-cervical structures about 2 years after a left radical nephrectomy. she underwent en-bloc resection of the massin conjunctionwith total ureterectomy, bladder cuff excision and hysterectomy.the patient was referred to oncology departm...

PURPOSE To analyze the optimum organ filling point for organs at risk (OARs) dose in cervical cancer high-dose-rate (HDR) brachytherapy. MATERIAL AND METHODS In a retrospective study, 32 locally advanced cervical cancer patients (97 insertions) who were treated with 3D conformal external beam radiation therapy (EBRT) and concurrent chemotherapy during 2010-2013 were included. Rotterdam HDR ta...

The purpose of this study was to investigate the concurrent effects of tandem length and bladder volume on dose to pelvic organs at risk (OARs) in HDR intracavitary brachytherapy treatment of cervical cancer. Twenty patients with locally advanced cervical cancer were selected for brachytherapy using Rotterdam applicators. The patients were CT scanned twice with empty and full bladder. Two treat...

BACKGROUND To retrospectively review the efficacy and organ preservation experience for muscle-invasive bladder cancer by trimodality therapy at our institution. METHODS Between July 2004 and February 2012, seventy patients (M/F = 55/15; median age = 69 years) of lymph node negative localized muscle-invasive bladder cancer were treated primarily with trimodality approach including transurethr...

we present a 55-year old male patient who was subjected to whole body skeletal scintigraphy for metastatic work up of urinary bladder cancer. whole body 99mtc-methylene diphosphonate (mdp) skeletal scintigraphy was performed. that revealed no skeletal metastasis in the entire body skeleton and normally visualized left kidney with empty right renal fossa. additionally tracer activity collected i...

Botulinum toxin is probably the newest addition in the treatment armamentarium for overactive bladder , but, despite its late FDA approval, a significant experience exists in several centers around the world with this type of treatment. Because of its experimental status, the treatment with botulinum toxin is still lacking the much needed standardization, allowing for a great variety when it co...

The purpose of this study was to quantify the relationship between treatment time and dose uncertainty due to intrafraction organ motion in prostate cancer radiotherapy (RT). Ten consecutive patients with prostate cancer treated by radical RT by volumetric modulated arc therapy (RapidArc) were considered. For each patient, pre- and post-treatment cone beam computed tomography (CBCT) was perform...

Background: Annual patient effective dose equivalent can be considered as a quantitative physical parameter describing the activities performed in each nuclear medicine department. Annual staff dose equivalent could be also considered as a parameter describing the amount of radiation risk for performing the activities. We calculated the staff to patient dose equivalent ratio to be used as a phy...