Sir, CTX-M-15 is an extended-spectrum b-lactamase (ESBL) extensively reported in humans, and in particular in Escherichia coli clones of sequence types (STs) ST131 and ST405. The blaCTX-M-15 gene has also become prevalent in Klebsiella pneumoniae, causing outbreaks in hospitals worldwide. – 4 In animals, a highly prevalent ESBL gene is the blaCTX-M-1 gene, with the blaCTX-M-15 gene also being f...

Extended-spectrum beta-lactamases (ESBL) mediating resistance to 3rd generation cephalosporins are a major public health issue. As food may be a vehicle in the spread of ESLB-producing bacteria, a study on the occurrence of cephalosporin-resistantu Escherichia coli in food was initiated. A total of 404 ESBL-producing isolates were obtained from animal-derived food samples (e.g., poultry product...

BACKGROUND Nosocomial infections caused by Pseudomonas aeruginosa presenting resistance to beta-lactam drugs are one of the most challenging targets for antimicrobial therapy, leading to substantial increase in mortality rates in hospitals worldwide. In this context, P. aeruginosa harboring acquired mechanisms of resistance, such as production of metallo-beta-lactamase (MBLs) and extended-spect...

Background: There are scarce reports about the association of Klebsiella oxytoca ( K. ) with urinary tract infection (UTI) in children. We aimed to evaluate prevalence fimA, mrkA, matB and pilQ adhesins genes extended-spectrum beta-lactamase (ESBL) blaCTX-M, blaTEM blaSHV by polymerase chain reaction (PCR) study biofilm formation antibiotics resistance from children UTI. Methods: This was a ret...

Background: The increasing pattern of Multi-Drug Resistant (MDR) bacteria has limited therapeutic options especially for nosocomial isolates of Klebsiella pneumoniae. Therefore, the aim of this study was the molecular detection of 16S rRNA methylase and blaCTX-M-15 among K. pneumoniae strains isolated from hospitalized patients in Mofid, Imam Hossein and Taleghani hospitals. Materials and Me...