Introduction: Alzheimer’s disease is a progressive neurodegenerative disorder, characterized by impairment of memory and changes in behavior and personality. Recent evidence suggests that mitochondrial channels play important roles in memory disorders. Accordingly, the biophysical properties of a single potassium channel were investigated in the brain mitochondrial inner membrane of rat with...

The Biophysical Chemistry Laboratory (BCL) was established in 1986 at Institute of Biochemistry and Biophysics (IBB), University of Tehran as the main base and the mother of biophysical chemistry in Iran. BCL is a famous worldwide research lab in the area of thermodynamics of protein denaturation and biomacromolecular interaction. The first student that joined BCL was MSc student in 1987, while...

Multiple myeloma, the second most common hematological cancer, is currently incurable due to refractory disease relapse and development of multiple drug resistance. We and others recently established the biophysical model that myeloma initiating (stem) cells (MICs) trigger the stiffening of their niches via SDF-1/CXCR4 paracrine; The stiffened niches then promote the colonogenesis of MICs and p...

make their red blood cells just go with the flow. the test could pinpoint those who may benefit from such therapies, putting more patients on treatment regimens that . can objectively identify patients who are not responding well to treatment or transfusion. Conversely, et al by Wood It may never be possible to predict the exact timing of vaso-occlusion, but the ex vivo biophysical test propose...

biophysical profile (bpp) test is the most commonly used antenatal test of fetal well-being. purpose of this study is determining the influence of acoustic stimulation (as) on bpp testing time. about 55 pregnant women at 35 to 42 weeks who referred to department of obstetric & gynecology at university of medical sciences, tabriz, iran, were selected randomly. we used abdominal ultrasound guidan...

With the ever-increasing number of satellites and the availability of data free of charge, the integration of multi-sensor images in coherent time series offers new opportunities for land cover and crop type classification. This article investigates the potential of structural biophysical variables as common parameters to consistently combine multi-sensor time series and to exploit them for lan...