OBJECTIVE To investigate the relation of methionine synthase (MS) gene variation with congenital heart disease (CHD) phenotype. METHODS One hundred and ninety three CHD patients (94 males and 99 females) and their biological parents (nuclear families) in Liaoning Province were selected as the case group, and another 104 normal persons (60 males and 44 females) and their parents without family...

BACKGROUND A longitudinal study was conducted to investigate the role of maladaptive parental behavior in the association between parent and offspring psychiatric disorder. METHODS Psychosocial and psychiatric interviews were administered to a representative community sample of 593 biological parents and their offspring from 2 counties in the state of New York in 1975, 1983, 1985 to 1986, and...

BACKGROUND Parents influence the physical activity and sedentary behaviour of their children. This analysis examines associations between parental role modeling and support and children's physical activity and sedentary behaviour. DATA AND METHODS The sample consists of 1,328 biological parent-child pairs from the first three cycles of the Canadian Health Measures Survey (2007 through 2013). ...

Research has increasingly focused on intentional or planned lesbian, gay, bisexual (LGB)parent families; however, how young adults in these families navigate the aftermath of parental break-up and subsequent repartnering is unexamined. This qualitative study of 20 young adults who had experienced their LGB parents’ relationship dissolution and/or the formation of an LGB stepfamily examined how ...

This study examines associations between maternal and paternal sensitive parenting and child cognitive development across the first 3 years of life using longitudinal data from 630 families with co-residing biological mothers and fathers. Sensitive parenting was measured by observational coding of parent-child interactions and child cognitive development was assessed with the Bayley Scales of I...

OBJECTIVE To determine whether familial risk of cancer is limited to early onset cases. DESIGN Nationwide prospective cohort study. SETTING Nationwide Swedish Family-Cancer Database. PARTICIPANTS All Swedes born after 1931 and their biological parents, totalling >12.2 million individuals, including >1.1 million cases of first primary cancer. MAIN OUTCOME MEASURES Familial risks of the c...

OBJECTIVE This study examined associations of asthma management-related beliefs and behaviors with immune markers and clinical outcomes in a sample of 66 children with asthma (ages 9-18 years). METHODS Children and parents were interviewed about asthma management beliefs and behaviors. Immune measures included stimulated production of cytokines implicated in asthmatic airway inflammation, eos...

The authors studied eight sets of healthy twins, ranging in physical maturity from prepubertal to late pubertal, and their parents, to assess psychological changes in early adolescence. A phase-specific psychosocial regression correlates with the biological onset of puberty. We present preliminary findings related to twinship, parental reactions, and longitudinal development, based on detailed ...

This study examines the causal link between parental non-marital relationship dissolution and the health status of young children. Using a representative sample of children all born out of wedlock drawn from the Fragile Families and Child Wellbeing Study, we investigate whether separation between unmarried biological parents has a causal effect on a child’s likelihood of developing asthma. Adop...

The salutary effects of being raised by two married, biological parents depend on the quality of care parents can provide. Using data from an epidemiological sample of 1,116 5-year-old twin pairs and their parents, this study found that the less time fathers lived with their children, the more conduct problems their children had, but only if the fathers engaged in low levels of antisocial behav...