small supernumerary marker chromosomes (ssmc) are still a major problem in clinical cytogenetics as they cannot be identified or characterized unambiguously by conventional cytogenetics alone. on the other hand, and perhaps more importantly in prenatal settings, there is a challenging situation for counseling how to predict the risk for an abnormal phenotype, especially in cases with a de novo ...

extant limpet. In addition, bivalves also acquired a novel structure, adducter muscle to close the separated shell plate. Because the two novel structures, the separated shell plate and the adducter muscle appear early embryonic stage, their evolution should be understood as a modification of early development. To understand the evolution of bivalve bodyplan, we have traced the cleavage pattern...

Despite advancements in detection and in treatment of this disease, prostate cancer death rates remain largely unchanged. This is largely due to the heterogeneous biology of prostate cancer, which is characterized by a wide spectrum of clinical behavior ranging from indolent to a rapidly progressing disease. In this manuscript we studied about molecular markers like p53 and MDR1 in prostate can...

Landscape genomics correlates genetic variation patterns with geographic variables to investigate how geographical and environmental characteristics affect the genetic structure of populations (Luikart et al., 2003; Joost et al., 2007; Holderegger & Wagner, 2008; Pariset et al., 2009; Shwartz et al., 2009). A field combining molecular markers, genetics and landscape structure was first describe...

The formation of the Brazilian Amazonian population has historically involved three main ethnic groups, Amerindian, African and European. This has resulted in genetic investigations having been carried out using classical polymorphisms and molecular markers. To better understand the genetic variability and the micro-evolutionary processes acting in human groups in the Brazilian Amazon region we...

The incorporation of plant biomass into soil usually leads to long-chain n-alkanes with a relative predominance of odd carbon numbered homologues. Contrastingly, an increase in short-chain even carbon numbered n-alkanes was found in charred biomass with progressing temperatures. We applied lipid analysis to buried ancient topsoils that contained charred organic matter and to corresponding contr...

The arachnid order Opiliones, and the suborder Cyphophthalmi in particular, have recently been used to test biogeographical patterns in Southeast Asia due to their ancient age and extremely low vagility. Here we report the first Cyphophthalmi—two juveniles—known from Mindanao in the southern Philippine Archipelago, and we place them in a molecular phylogeny to test biogeographical hypotheses fo...