Preparation, properties, and some of the applications of heterochain polymers, related to biologically active or medical materials, are discussed. Various examples of the polymerization processes of the monomers containing 0,5—, N— a.o. heteroatoms in the ring are considered together with some peculiarities of the resulting polymers. The presence of the heteroatoms in the polymer chains makes t...

Lactoperoxidase (LPO E.C. 1.11.1.7) is a member of the peroxidase family and an important glycoprotein containing heme group in its structure showing antimicrobial effect on disease causing microorganisms digestive system newborn babies. Thiazoles are simplest members heterocyclic compounds nitrogen sulfur atoms their structure. Many active pharmaceutical substances such as vitamin B1, penicill...

New 3(2H)-pyridazinone derivatives containing a N'-benzyliden-acetohydrazide moiety at position 2 were synthesized. The structures of these newly synthesized compounds were confirmed by IR, 1H NMR, and MS data. These compounds were tested for their antibacterial, antifungal, antimycobacterial, and cytotoxic activities. The compounds 2-[4-(4-chlorophenyl)-6-(morpholin-4-yl)-3-oxo-(2H)-pyridazin-...

This paper presents some results concerning the immobilization through chemical bonds of some biologically active compounds on the maleic anhydridemethyl methacrylate) copolymer. The high reactivity of the anhydride cycle of the polymer has allowed us to obtain conjugates in which the biologically active compounds of some heterocyclic compounds are immobilized on the polymeric support through a...

The application of N-heterocyclic carbene complexes as active sites in materials other than catalysis has been remarkably scarce. Inspired by the - often misleading - 'carbene' label, which implies a substantial degree of M = C pi bonding, we have been interested in evaluating the potential of N-heterocyclic carbene complexes as building blocks for constructing electronically active materials. ...

Thioenethiophene derivatives represent an important class of compounds with diverse biological activities. We describe here the synthesis of a new series of thieno[2,3-b]thiophene containing bis-heterocyclic compounds 3-7. All the compounds were evaluated for their in vitro antioxidant potential, α-glucosidase and β-glucuronidase inhibiton and anticancer activity against PC-3 cell lines. Compou...