Electropermeabilization (EP) based protocols such as those applied in medicine, food processing or environmental management, are well established and widely used. The applied voltage, as well as tissue electric conductivity, are of utmost importance for assessing final electropermeabilized area and thus EP effectiveness. Experimental results from literature report that, under certain EP protoco...

Interrelation of skin temperature and blood flow oscillations of fingers under normal conditions in healthy subjects has been investigated. Oscillations of a blood flow were measured by means of photoplethysmography; oscillations of a temperature were registered by means of thermal imaging camera. The method of blood flow reconstruction by temperature oscillations with the use of the Pennes bio...

PURPOSE The thermal effect of the intramyocardial blood perfusion on the size of lesions created by radiofrequency cardiac ablation (RFCA) has not been adequately studied to date. Our objective was to assess the impact of including this phenomenon in RFCA computer modelling in terms of the thermal lesion depth created. METHODS A computer model was built and computer simulations were conducted...

The dynamic nature of blood flow during hyperthermia therapy has made the control of minimum tumor temperature a difficult task. This paper presents initial studies of a novel approach to closed-loop control of local minimum tissue temperatures utilizing a newly developed estimation algorithm for use with conductive interstitial heating systems. The local minimum tumor temperature is explicitly...

Laser-induced thermotherapy (LITT) is a minimally invasive laser hyperthermia procedure for the treatment of localized tumors. Mathematical modeling of the photothermal processes in laser-irradiated tissues is essential for optimal treatment planning. In this study, A Monte Carlo method is introduced to simulate photon transport in the tumor tissues with complex geometries. The dual reciprocity...

Objective To create an improved planning method for pediatric regional hyperthermia (RHT) using the SIGMA-30 applicator (SIGMA-30).Materials and Methods An electromagnetic model of was generated use with finite-difference time-domain (FDTD) method. Applying special MATLAB-based algorithms, voxel models a patient pelvic rhabdomyosarcoma were created from Computed-Tomography (CT) contours FDTD (F...

A boundary element method is applied for the numerical solution of a boundary value problem for a two-dimensional steady-state bioheat transfer model of the human eye. The human eye is modeled as comprising four distinct homogeneous regions. The boundary condition on the outer surface of the cornea is non-linear due to heat radiation. An iterative approach is used to treat the non-linear heat r...

Understanding thermal transport and temperature distribution within biological organs is important for therapeutic aspects related to hyperthermia treatments such as radiofrequency ablation (RFA). Unlike surface heating, the RFA treatment volumetrically heats up the biological media using a heating probe which provides the input energy. In this situation, the shape of the affected region is ann...