Both benzo[a]pyrene (BaP) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are potent ligands of aryl hydrocarbon receptors (AhR). Although animal studies indicate that both compounds induce pathological changes in the peripheral lung, the specific cell type involved remains unclear. Clara cells, expressing Clara cell specific protein (CCSP) and abundant in cytochrome P450, are nonciliated bronch...

The present work was performed to determine the impacts of commercial disinfectants against biomass, viability, and biochemical composition Salmonella enterica serovar Thyphimurium ATCC14028 biofilm. biofilm grown in microplates exposed namely sodium hypochlorite, benzalkonium chloride, chloroxylenol, dodecyl-benzene sulfonate-based disinfectants. Biofilm were determined using crystal violet as...

OBJECTIVE Apathetic hyperthyroidism can be misdiagnosed or diagnosed late, and older patients are often susceptible to adverse effects of treatment for thyrotoxicosis. The aim of this study was to identify factors associated with apathetic hyperthyroidism. METHODS We retrospectively examined serum calcium, phosphorus and bone-specific alkaline phosphatase (BAP) levels and thyroid-associated v...

Although inserting exogenous viral genome segments into rotavirus particles remains a hard challenge, this study describes the in vivo incorporation of a recombinant viral capsid protein (VP6) into newly assembled rotavirus particles. In vivo biotinylation technology was exploited to biotinylate a recombinant VP6 protein fused to a 15 aa biotin-acceptor peptide (BAP) by the bacterial biotin lig...

The main objective of this study was to assess the annual concentration and seasonal variation of benzo(a)pyrene (BaP) associated with PM10 in an urban site of Győr and in a rural site of Sarród in the sampling period of 2008–2012. A total of 280 PM10 aerosol samples were collected in each sampling site and analyzed for BaP by gas chromatography method. The BaP concentrations ranged from undete...

background: measuring of maternal serum pregnancy-associated plasma protein-a (papp-a) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta.objective: the aim was to determination of association between placental thickness in second trimester with low level of papp-a in first trimester.materials and methods: in this cohort study, serum papp-a of...

BACKGROUND Recently, an increasing number of human and animal studies have reported that exposure to benzo(a)pyrene (BaP) induces neurological abnormalities and is also associated with adverse effects, such as tumor formation, immunosuppression, teratogenicity, and hormonal disorders. However, the exact mechanisms underlying BaP-induced impairment of neurological function remain unclear. The ai...

Fish have defense systems that are capable of repairing damages caused by xenobiotics like benzo[a]pyrene (BaP), so the aims this study were to identify BaP toxicity in melanomacrophages (MMs) cytoskeleton, evaluate melanin area MMs, and analyze genotoxicity. Rainbow trout juveniles (n = 24) split 48h 7d treatments received 2 mg/kg BaP. After experiment, blood samples collected liver was remove...

V. cholerae can form sessile biofilms associated with abiotic surfaces, cyanobacteria, zoo-plankton, mollusks, or crustaceans. Along with the vibrio polysaccharide, secreted proteins of the rbm gene cluster are key to the biofilm ultrastructure. Here we provide a thorough structural characterization of RbmA, a protein involved in mediating cell-cell and cell-biofilm contacts. We correlate our s...

conclusions: it can be concluded that most of a. baumannii isolates can form biofilm in microtiter plate and tube. the results also verified that most of these isolates were resistant to ciprofloxacin and imipenem. results: results showed that in tube method under shaking, 22% of clinical isolates were strong biofilm producers while 23% of them were not able to form biofilms. in this experiment...