The past decade has witnessed an emerging and fast-growing field on mechanically soft systems, ranging from materials (e.g. hydrogels) to devices flexible electronics), functional systems robotics). It is envisioned that will continue thrive in the coming decades academia industrial communities. launch of Soft Science provide first dedicated platform for publishing research findings share knowl...

Abstract This review is dedicated to electronics materials enabling thin‐film‐based neural interface and bioelectronics devices. First‐generation bioelectronic medicine devices feature hand‐crafted bulk electrodes, wires interconnects, insulators. discusses how modern science, especially know‐how repurposed from semiconductor microdevice technologies, enables next‐generation bioelectronics. Tho...

A single-biomolecule optical toggle-switch is demonstrated based on a mutated green fluorescent protein (GFP). We have exploited molecular biology techniques to tailor GFP molecular structure and photophysical properties and give it optically-controlled bistability between two distinct states. We present optical control of the fluorescence dynamics with two laser beams at 476 and 350 nm down to...

An on/off-switchable graphene-based zipper-like interface is architectured for efficient bioelectrocatalysis. The graphene interface transduces a temperature input signal into structural changes of the membrane, resulting in the amplification of electrochemical signals and their transformation into the gated transport of molecules through the membrane.

Understanding the interaction between the biological environment (tissues, cells, proteins, electrolytes, etc.) and a solid surface is crucial for biomedical applications such as bio-sensors, bio-electronics, tissue engineering and the optimization of implant materials. Cells, the cornerstones of living tissue, perceive their surroundings and subsequently modify it by producing extracellular ma...

Three-dimensional (3D) printing is an innovative additive manufacturing technology, capable of fabricating unique structures in a layer-by-layer manner. Semi-solid extrusion (SSE) subset material 3D printing, and through the sequential deposition layers gel or paste creates objects any desired size shape. In comparison to other extrusion-based technologies, SSE employs low temperatures which ma...

Enzymatic biofuel cells (EBFCs) are a subgroup of fuel that use enzymes as catalysts. EBFCs utilize physiological substrates such glucose or lactate great interest implantable wearable power sources to activate medical devices. This contribution introduces the working principles and summarizes recent progress in EBFC-enabled biosensors, pulse generators, therapy. Biosensors with self-powered ch...