A principal requirement for biomedical alloys in device implantation is in vivo corrosion resistance, and optimal compatibility at the implant interface. In the context of materials science, biocompatibility is the ability of a material to assist a specific biological application and elicit an appropriate response, simulated in vitro or translated in vivo. The in vivo response of a device is de...

Patients treated with peritoneal dialysis (PD) are at risk for development of ultrafiltration failure and peritonitis. The relative unphysiologic composition of the currently used peritoneal dialysis fluids (PDF) is a major cause for the development of morphologic changes of the peritoneal membrane such as fibrosis and new vessel formation, ultimately resulting in ultrafiltration failure. In re...

The functionalization of gold nanorods (GNRs) with polymers is essential for both their colloidal stability and biocompatibility. However, a bilayer of the toxic cationic surfactant cetyl trimethylammonium bromide (CTAB) adsorbed on the nanorods complicates this process. Herein, we report on a strategy for the biocompatible functionalization of GNRs with a hydrophobic polymeric precursor, polyv...

Purpose: This study sought to compare the elemental constitution, morphological characteristics, particle size distribution, biocompatibility, and mineralization potential of Ortho MTA (OMTA) and ProRoot MTA (PMTA). Materials and Methods: OMTA and PMTA were compared using energy-dispersive spectrometry, particle size analysis, and scanning electron microscopy. The biocompatibility and mineraliz...

Stent implantation represents a major step forward since the introduction of coronary angioplasty. As indications continue to expand, better understanding of the early and late biocompatibility issues appears critical. Persisting challenges to the use of intracoronary stents include the prevention of early thrombus formation and late neointima development. Different metals and designs have been...

BACKGROUND The past years have seen the development of many synthetic bone replacements. To test their biocompatibility and ability for osseointegration, osseoinduction and -conduction requires their placement within bone preferably in an animal experiment of a higher species. METHODS A suitable experimental animal model in sheep with drill holes of 8 mm diameter and 13 mm depth within the pr...

The use of metals and their alloys in restorative and implant dentistry dates back to centuries. Titanium (Ti) is one of the most widely used biomaterial for medical implants because of its excellent mechanical properties and exceptional biocompatibility. The good biocompatibility of Ti is related to the thin oxide layer formed on Ti surface. TiO2 is inactive with the surrounding biological env...

The filter membrane in a CRRT extracorporeal circuit is vitally important for several reasons. Because it has the largest degree of exposure to blood of all circuit components, the membrane is the most important determinant of the circuit’s overall biocompatibility. In addition, membrane characteristics determine both the solute removal and water permeability properties of a CRRT filter. The fo...

Up to now, there are enormous efforts to develop such coatings that can enhance the biocompatibility properties of metallic implant materials (Ti, Ti6Al4V, CoCrMo, stainless steel) and even provide antimicrobial effect. The most interesting candidates for these coatings are calcium phosphate (CaP) or specifically hydroxyapatite (HAp) phases due to their biocompatibility, osteoconductive propert...