background and objectives: in the present study, isolation of streptomyces associated with marine sponges and its bioactive potential against fish and shellfish pathogens were assessed. the streptomyces sp. were isolated from the marine sponges namely callyspongia diffusa, mycale mytilorum, tedania anhelans and dysidea fragilis collected from vizhinjam port, situated in the south-west coast of ...

generation neural stem cells from neurosphere–derived bone marrow stem cells using bioactive substance atc. bone marrow cells (bmscs) were isolated from rat. bmscs cultured by dmem/f12 medium supplemented with 10% fetal bovine serum. these cells evaluated by specific markers of bmscs such as bioactive substance atc, b27. then bmscs differentionated in to neurosphere and divided in two groups wh...

in this study the bacterial growth inhibitory activity of peptide fragments produced from goat’s milk whey proteins by enzymatic hydrolysis using trypsin, ficin and a combination of both was investigated. goat’s milk whey proteins were isolated and subjected to enzymatic hydrolysis and peptides were purified by ultrafiltration followed by reverse-phase high-performance liquid chromatography (rp...

liposomes have attracted great interest as efficient carriers for nutrients, drugs and other bioactive agents as well as ideal models for biological membranes. this article intends to provide an overview of liposomes and nanoliposomes definition as well as their properties and preparation methods. also it elaborates on various applications of nanoliposomes in nanotherapy including diagnostics, ...

screening of microorganisms for the production of novel antibiotics has been intensivelypursued for many years by scientists. actinomycetes have the capability to synthesize manydifferent antibiotics. a total of 69 actinomycete isolates were recovered from soil samplescollected from alborz province. selected colonies (rough, chalky) of actinomycetes werepurified. all screened isolates were iden...

The cytotoxicity of the biomaterials is a key issue that should be addressed prior to pre-clinical applications. This study was designed to evaluate and compare the cytotoxixity of two forms of bioactive glasses:nanopowder:andmicropowder. Human HGF1-PI53 gingival fibroblast cells were used to evaluate the cytotoxicity of 0.5, 1, 1.5, 2, 5, 10, 15 and 20 mg/mL concentrations of the two bioactive...

Introduction: The aim of this study was to evaluate the sealing ability of Bioactive glass (BG) and Bioactive glass-Hydroxyapatite (BG-HA) in comparison to Mineral Trioxide Aggregate (MTA). Methods: The sealing ability of Bioactive glass and Bioactive glass-hydroxyapatite mixed with glass ionomer cement and Mineral Trioxide Aggregate used as retrograde filling material was assessed by bacterial...

Bioactive ceramics have been used clinically to repair bone defects owing to their biological affinity to living bone; i.e. the capability of direct bonding to living bone, their so-called bioactivity. However, currently available bioactive ceramics do not satisfy every clinical application. Therefore, the development of novel design of bioactive materials is necessary. Bioactive ceramics show ...