cauliflower-like nanostructure of cadmium oxide was synthesized by utilizing mechanochemical reaction followed calcination procedure for the first time. the design of experiment (doe) by taguchi method was used to study influence of the chosen factors and to consider optimum conditions of the experiments. the temperature of calcining, the duration of milling, the duration of calcining and react...

The aim of this research is to study Ni2+ supported on hydroxyapatite-core-shell magnetic γ-Fe2O3 nanoparticles (γ-Fe2O3@HAp-Ni2+) as a green and recyclable catalyst for the Biginelli reaction under solvent-free conditions. One-pot multi-component condensation of 1,3-dicarbonyl compounds, urea and aldehydes at 80 oC affords the corresponding compounds in high yields and in short reaction times ...

Bioactive dihydropyrimidinones (DHPs) were designed and synthesized by a multicomponent Biginelli reaction. The reaction was catalyzed the polarized surface of nano-zirconium dioxide with partial positive charge 0.52e at Zr center negative ?0.23e oxygen center. There good corroboration between computed experimental ZrO2 cell parameters bond distances as determined in silico vitro methods. Since...

Biginelli dihydropyrimidinone derivatives as structural analogs of monastrol, a known human kinesin Eg5 inhibitor, were synthesized. IC50 values of the synthesized compounds against the proliferation of human hepatocellular carcinoma and human epithelial carcinoma cell lines were determined through MTT assay. Molecular docking study gave a clear insight into the structural activity relationship...